The vitronectin-binding domain of plasminogen activator inhibitor-1 plays an important functional role in lipopolysaccharide-induced lethality in mice

被引：5
|
作者：
Narasaki, R. [1 ]
Xu, Z. [1 ]
Liang, Z. [1 ]
Fung, L. C. W. [1 ]
Donahue, D. [1 ]
Castellino, F. J. [1 ,2 ]
Ploplis, V. A. [1 ,2 ]
机构：
[1] Univ Notre Dame, WM Keck Ctr Transgene Res, Notre Dame, IN 46556 USA
[2] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
来源：
JOURNAL OF THROMBOSIS AND HAEMOSTASIS | 2012年 / 10卷 / 12期
关键词：
ENDOTHELIAL-CELLS; NEUTROPHIL APOPTOSIS; SIGNALING PATHWAYS; PAI-1; RECEPTOR; LOCALIZATION; CHEMOTAXIS; EXPRESSION; MIGRATION; ADHESION;
D O I：
10.1111/jth.12032
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Narasaki R, Xu Z, Liang Z, Fung LCW, Donahue D, Castellino FJ, Ploplis VA. The vitronectin-binding domain of plasminogen activator inhibitor-1 plays an important functional role in lipopolysaccharide-induced lethality in mice. J Thromb Haemost 2012; 10: 267821.
引用
收藏
页码：2618 / 2621
页数：4
相关论文
共 50 条
  • [1] LOCALIZATION OF VITRONECTIN BINDING DOMAIN IN PLASMINOGEN-ACTIVATOR INHIBITOR-1
    LAWRENCE, DA
    BERKENPAS, MB
    PALANIAPPAN, S
    GINSBURG, D
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, 269 (21) : 15223 - 15228
  • [2] Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin
    Department of Vascular Biology, Scripps Research Institute, San Diego, CA 92037, United States
    不详
    J. Biol. Chem., 22 (12716-12723):
  • [3] Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin
    Deng, G
    Royle, G
    Wang, S
    Crain, K
    Loskutoff, DJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (22) : 12716 - 12723
  • [4] Role of plasminogen activator inhibitor-1 and vitronectin in the response to arterial injury in mice
    Konstantinides, S
    Schafer, K
    Thinnes, T
    Loskutoff, DJ
    CIRCULATION, 1999, 100 (18) : 703 - 703
  • [5] Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin
    Deng, G
    Curriden, SA
    Hu, G
    Czekay, RP
    Loskutoff, DJ
    JOURNAL OF CELLULAR PHYSIOLOGY, 2001, 189 (01) : 23 - 33
  • [6] LOCALIZATION OF A VITRONECTIN BINDING REGION OF PLASMINOGEN-ACTIVATOR INHIBITOR-1
    PADMANABHAN, J
    SANE, DC
    THROMBOSIS AND HAEMOSTASIS, 1995, 73 (05) : 829 - 834
  • [7] IDENTIFICATION OF THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 BINDING HEPTAPEPTIDE IN VITRONECTIN
    MIMURO, J
    MURAMATSU, S
    KURANO, Y
    UCHIDA, Y
    IKADAI, H
    WATANABE, S
    SAKATA, Y
    BIOCHEMISTRY, 1993, 32 (09) : 2314 - 2320
  • [8] Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
    Eitzman, DT
    Westrick, RJ
    Nabel, EG
    Ginsburg, D
    BLOOD, 2000, 95 (02) : 577 - 580
  • [9] Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin
    Lazar, MH
    Christensen, PJ
    Du, M
    Yu, B
    Subbotina, NM
    Hanson, KE
    Hansen, JM
    White, ES
    Simon, RH
    Sisson, TH
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2004, 31 (06) : 672 - 678
  • [10] IDENTIFICATION OF THE VITRONECTIN BINDING DOMAIN IN PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) BY RANDOM MUTAGENESIS
    LAWRENCE, DA
    BERKENPAS, MB
    PALANIAPPAN, S
    GINSBURG, D
    BLOOD, 1993, 82 (10) : A451 - A451
12345