Vitamin-D measurement in patients with adolescent idiopathic scoliosis

被引:38
作者
Balioglu, Mehmet B. [1 ]
Aydin, Canan [2 ]
Kargin, Deniz [1 ]
Albayrak, Akif [1 ]
Atici, Yunus [1 ]
Tas, Suleyman K. [1 ]
Kaygusuz, Mehmet A. [1 ]
机构
[1] MH Metin Sabanci Baltalimani Bone Dis Training &, Dept Orthopaed & Traumatol, Rumeli Hisari Caddesi 62, TR-34470 Istanbul, Turkey
[2] MH Metin Sabanci Baltalimani Bone Dis Training &, Dept Sports Med, Istanbul, Turkey
来源
JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B | 2017年 / 26卷 / 01期
关键词
adolescent idiopathic scoliosis; Cobb's angle; vitamin D; vitamin-D deficiency; BONE-MINERAL DENSITY; D-RECEPTOR; D-DEFICIENCY; POLYMORPHISM; FRACTURE; OUTCOMES;
D O I
10.1097/BPB.0000000000000320
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Our retrospective study compared vitamin-D levels in 229 patients with adolescent idiopathic scoliosis (AIS) and 389 age-matched controls, and evaluated the correlation between vitamin-D levels and sex, Cobb's angle, and serum levels of calcium (Ca), phosphorus, and alkaline phosphatase in the AIS group. Vitamin-D levels were lower in the AIS group, with no sex-specific effects, indicative of a possible vitamin-D resistance in AIS. Vitamin-D levels correlated positively with Ca levels and negatively with Cobb's angle, indicative of a possible role of vitamin D in the etiopathogenesis of AIS. Patients with AIS should be monitored for vitamin-D deficiency/insufficiency.
引用
收藏
页码:48 / 52
页数:5
相关论文
共 27 条
[1]   Vitamin D action and regulation of bone remodeling: Suppression of osteoclastogenesis by the mature osteoblast [J].
Baldock, Paul A. ;
Thomas, Gethin P. ;
Hodge, Jason M. ;
Baker, Sara U. K. ;
Dressel, Uwe ;
O'Loughlin, Peter D. ;
Nicholson, Geoffrey C. ;
Briffa, Kathy H. ;
Eisman, John A. ;
Gardiner, Edith M. .
JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 (10) :1618-1626
[2]   Association between vitamin D receptor gene polymorphisms, falls, balance and muscle power: results from two independent studies (APOSS and OPUS) [J].
Barr, R. ;
Macdonald, H. ;
Stewart, A. ;
McGuigan, F. ;
Rogers, A. ;
Eastell, R. ;
Felsenberg, D. ;
Glueer, C. ;
Roux, C. ;
Reid, D. M. .
OSTEOPOROSIS INTERNATIONAL, 2010, 21 (03) :457-466
[3]  
Batista Rodrigo Martins Borges Ferreira, 2014, Coluna/Columna, V13, P275, DOI 10.1590/S1808-18512014130400432
[4]   Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes [J].
Bischoff-Ferrari, Heike A. ;
Giovannucci, Edward ;
Willett, Walter C. ;
Dietrich, Thomas ;
Dawson-Hughes, Bess .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 84 (01) :18-28
[5]   Hypovitaminosis D in Patients Scheduled to Undergo Orthopaedic Surgery A Single-Center Analysis [J].
Bogunovic, Ljiljana ;
Kim, Abraham D. ;
Beamer, Brandon S. ;
Nguyen, Joseph ;
Lane, Joseph M. .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2010, 92A (13) :2300-2304
[6]   Persistent osteopenia in adolescent idiopathic scoliosis - A longitudinal follow-up study [J].
Cheng, JCY ;
Guo, X ;
Sher, AHL .
SPINE, 1999, 24 (12) :1218-1222
[7]   Generalized low areal and volumetric bone mineral density in adolescent idiopathic scoliosis [J].
Cheng, JCY ;
Qin, L ;
Cheung, CSK ;
Sher, AHL ;
Lee, KM ;
Ng, SWE ;
Guo, X .
JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 (08) :1587-1595
[8]   Association between osteoprotegerin gene polymorphism and bone mineral density in patients with adolescent idiopathic scoliosis [J].
Eun, Il-Soo ;
Park, Weon Wook ;
Suh, Kuen Tak ;
Kim, Jeung Il ;
Lee, Jung Sub .
EUROPEAN SPINE JOURNAL, 2009, 18 (12) :1936-1940
[9]   Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly [J].
Fang, Y ;
Van Meurs, JBJ ;
Bergink, AP ;
Hofman, A ;
Van Duijn, CM ;
Van Leeuwen, JP ;
Ap Pols, H ;
Uitterlinden, AG .
JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 (09) :1632-1641
[10]   Vitamin D deficiency [J].
Holick, Michael F. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (03) :266-281