The Seventh Pandemic Vibrio cholerae O1 El Tor Isolate in China Has Undergone Genetic Shifts

被引:10
|
作者
Zhang, Ping [1 ,2 ]
Li, Fengjuan [1 ,2 ]
Liang, Weili [1 ,2 ]
Li, Jie [1 ,2 ]
Kan, Biao [1 ,2 ]
Wang, Duochun [1 ,2 ]
机构
[1] Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China
[2] Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
CLASSICAL BIOTYPE; EASTERN INDIA; VARIANT; TOXIN; STRAINS; BANGLADESH; VIRULENCE; OUTBREAK; CTXB;
D O I
10.1128/JCM.03121-13
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A total of 330 clinical Vibrio cholerae O1 serogroups from China dating between 1961 and 2010 were investigated. By phenotypic biotyping and genetic analysis, during the seventh pandemic of V. cholerae O1 in China, the isolates of hybrid biotype (mixed classical phenotypes) were present during the entire 1961-2010 period, while El Tor genetic shifts appeared in 1992 and replaced the prototype El Tor from 2002 to 2010.
引用
收藏
页码:964 / 967
页数:4
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