The effect of a type I photoinitiator on cure kinetics and cell toxicity in projection-microstereolithography

被引：31

作者：

Bail, R. ^{[1
]}

Patel, A.

Yang, H. ^{[1
]}

Rogers, C. M.

Rose, F. R. A. J.

Segal, J. I. ^{[1
]}

Ratchev, S. M. ^{[1
]}

机构：

[1] Univ Nottingham, Fac Engn, Mfg Res Div, Nottingham NG7 2RD, England

来源：

FIRST CIRP CONFERENCE ON BIOMANUFACTURING | 2013年 / 5卷

基金：

英国工程与自然科学研究理事会;

关键词：

Microstereolithography; photopolymerization; photoinitiator; BAPO; FTIR; Alamar Blue assay; MICRO-STEREOLITHOGRAPHY; DENTAL RESINS;

D O I：

10.1016/j.procir.2013.01.044

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Projection-microstereolithography is an additive manufacturing technique based on the spatially controlled solidification of a liquid photopolymer on exposure to digitally manipulated light patterns. This study presents a methodology to evaluate the effect of a type-I photoinitiator on the reaction kinetics in the process and the cytocompatibility of the produced components. While the reaction speed and degree of conversion were heavily dependent on the applied amount of the initiator, a clear toxic effect was observed with all tested concentrations, and a post-processing step of 7 days was required to leach out the initiator residues. (C) 2013 The Authors. Published by Elsevier B.V. Selection and/or peer-review under responsibility of Professor Mamoru Mitsuishi and Professor Paulo Bartolo

引用

页码：222 / 225

页数：4

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