Necrobiotic xanthogranuloma without paraproteinemia

被引：2

作者：

Macedo, Danielle Mazziero ^{[1
]}

Hirata, Sergio Henrique ^{[1
]}

Michalany, Nilceo S. ^{[2
]}

Simoes e Silva Enokihara, Milvia Maria ^{[1
]}

Enokihara, Mauro Y. ^{[1
]}

机构：

[1] Univ Fed Sao Paulo, Escola Paulista Med, Dept Dermatol, Sao Paulo, Brazil

[2] Univ Fed Sao Paulo, Escola Paulista Med, Dept Patol, Sao Paulo, Brazil

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2008年 / 83卷 / 03期

关键词：

granuloma; paraproteinemias; skin diseases; metabolic; xanthomatosis;

D O I：

10.1590/S0365-05962008000300009

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Necrobiotic xanthogranuloma is a chronic granulomatous and xantomathous disease, characterized by indurated, nontender, yellowish and erythematous nodules and plaques especially located on the periorbital region. It is commonly associated with paraproteinemia and an increased risk for hematological and lymphoproliferative malignancies. Its pathogenesis remains unclear Alkylating agents, such as chlorambucil and melphalan may be used to treat the disease with variable success. We report a case of this rare disease in a patient with a solitary tumor and without paraproteinemia.

引用

页码：243 / 246

页数：4

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