DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages

被引:10
作者
Williams-DeVane, ClarLynda R. [1 ]
Wolf, Maritja A. [2 ]
Richard, Ann M. [1 ]
机构
[1] US EPA, Off Res & Dev, Natl Ctr Computat Toxicol, Washington, DC USA
[2] Lockheed Martin, Res Triangle Pk, NC 27711 USA
关键词
D O I
10.1093/bioinformatics/btp042
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Distributed Structure-Searchable Toxicity (DSSTox) ARYEXP and GEOGSE files are newly published, structure-annotated files of the chemical-associated and chemical exposure-related summary experimental content contained in the ArrayExpress Repository and Gene Expression Omnibus (GEO) Series (based on data extracted on September 20, 2008). ARYEXP and GEOGSE contain 887 and 1064 unique chemical substances mapped to 1835 and 2381 chemical exposure-related experiment accession IDs, respectively. The standardized files allow one to assess, compare and search the chemical content in each resource, in the context of the larger DSSTox toxicology data network, as well as across large public cheminformatics resources such as PubChem (http://pubchem.ncbi.nlm.nih.gov).
引用
收藏
页码:692 / 694
页数:3
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