Thalidomide in Behcet's disease

被引：27

作者：

Shek, LPC ^{[1
]}

Lim, DLC ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Paediat, Singapore 119074, Singapore

来源：

BIOMEDICINE & PHARMACOTHERAPY | 2002年 / 56卷 / 01期

关键词：

Behcet's disease; review; thalidomide;

D O I：

10.1016/S0753-3322(01)00154-8

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Behcet's disease is a chronic relapsing multisystem disease of unknown aetiology. It has a relapsing cyclical course, and is characterized by the triad of aphthous stomatitis, genital ulcerations and uveitis. There is familial and geographical clustering of cases, especially around the Mediterranean, the Middle East and East Asia. The condition is uncommon, but lesions sometimes are recalcitrant and can be debilitating to the affected individual. The treatment of Behcet's currently involves the use of steroids, immunomodulaters and immunosuppressives. Thalidomide has been used in cases of Behcet's disease with some success. This review will discuss Behcet's disease and the current information we have about using thalidomide for its treatment. (C) 2002 Editions scientifiques et medicales Elsevier SAS.

引用

页码：31 / 35

页数：5

共 48 条

[1]

[Anonymous], 1997, APLAR J RHEUMATOL

[2] A study of the cutaneous manifestations of Behcet's disease in patients from the United States [J].

Balabanova, M ;

Calamia, KT ;

Perniciaro, C ;

O'Duffy, JD .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 41 (04) :540-545

[3]

Behçet H, 1937, DERMATOL WOCHENSCHR, V105, P1152

[4]

Behcet's Disease Research Committee of Japan, 1974, JPN J OPHTHALMOL, V18, P291

[5] BEHCETS DISEASE - REPORT OF 41 CASES AND A REVIEW OF LITERATURE [J].

CHAJEK, T ;

FAINARU, M .

MEDICINE, 1975, 54 (03) :179-196

[6]

DAVATCHI F, 1993, INT CONGR SER, V1037, P225

[7]

Dilsen N, 1996, REV RHUM, V63, P512

[8] RECURRENT APHTHOUS STOMATITIS OF THE BEHCETS TYPE - SUCCESSFUL TREATMENT WITH THALIDOMIDE [J].

EISENBUD, L ;

HOROWITZ, I ;

KAY, B .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1987, 64 (03) :289-292

[9] INHIBITION OF PMN LEUKOCYTES CHEMOTAXIS BY THALIDOMIDE [J].

FAURE, M ;

THIVOLET, J ;

GAUCHERAND, M .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1980, 269 (03) :275-280

[10] CLINICAL-EXPERIENCE WITH THALIDOMIDE IN THE MANAGEMENT OF SEVERE ORAL AND GENITAL ULCERATION IN CONDITIONS SUCH AS BEHCETS-DISEASE - USE OF NEUROPHYSIOLOGICAL STUDIES TO DETECT THALIDOMIDE NEUROPATHY [J].

GARDNERMEDWIN, JMM ;

SMITH, NJ ;

POWELL, RJ .

ANNALS OF THE RHEUMATIC DISEASES, 1994, 53 (12) :828-832

← 1 2 3 4 5 →