Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation

被引：6

作者：

Fender, Erin A. ^{[1
]}

Kiani, Jawad G. ^{[1
]}

Holmes, David R., Jr. ^{[1
]}

机构：

[1] Mayo Clin, Dept Cardiovasc Dis, 200 1st St SW, Rochester, MN 55905 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2016年 / 18卷 / 11期

关键词：

Left atrial appendage closure; Watchman; Lariat; Atrial fibrillation; Stroke; AMPLATZER CARDIAC PLUG; WATCHMAN DEVICE; WARFARIN; RISK; ANTICOAGULATION; OCCLUSION; CONTRAINDICATIONS; OBLITERATION; FEASIBILITY; MULTICENTER;

D O I：

10.1007/s11883-016-0616-z

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Purpose of Review Anticoagulant therapy effectively reduces the incidence of stroke in patients with atrial fibrillation (AF) but is underutilized and frequently contraindicated. The left atrial appendage (LAA) is the primary site of thrombus formation in AF patients. Surgical and percutaneous appendage closure has been evaluated as a site-specific therapy to reduce systemic thromboembolism. Recent Findings We will review LAA closure techniques, examine recent outcome data, and discuss the indications for, and potential complications of, each approach. Summary Randomized data examining surgical LAA closure and epicardial closure with the LARIAT device are lacking. High quality, randomized data supports the efficacy of the WATCHMAN device for stroke prevention in patients with AF.

引用

页数：8

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