Effect of a hypocaloric diet with a commertial formula in weight loss and quality of life in obese patients with chronic osteoarthritis

Background: The aim of our study was to evaluate in patients with obesity and chronic osteoarthritis the impact on quality of life and metabolic control of a dietary intervention with a hypocaloric commercial formula. Methods: A sample of 55 obese patients with chronic osteoarthritis was enrolled. The study consisted of a 12-week weight reduction program where the participants received an oral diet replaced with 2 bricks of Optisource Plus (R). Results: In order to assess the effect of weight loss on different parameters, patients were divided in two groups by the median of weight loss percentage (9%); group 1 (< 9%) and group 2 (> 9%). In group 2, patients showed an improvement in total SF-36 score (4.0 +/- 6.1 points), physical function domain of SF 36(1.8 +/- 3.4 points), role physical domain of SF 36 (0.6 +/- 1.6 points) and vitality domain of SF 36 (2.7 +/- 4.6 points) improved. Total score of WOMAC test (- 8.2 +/- 15.0 points), function domain of WOMAC test (- 6.5 +/- 10.6 points) and stiffness domain of WOMAC test (-0.7 +/- 2.1 points) improved, too. Conclusion: The effect on metabolic response, functionality and quality of life was better in patients with a percentage of weight loss > 9% than patients with a lower weight loss. (Nutr Hosp. 2012;27:1648-1654) DOI:10.3305/nh.2012.27.5.6053