Local anesthetics take a central action in analgesia

被引:6
作者
Zeilhofer, Hanns Ulrich [1 ,2 ]
Schmelz, Martin [3 ]
机构
[1] Univ Zurich, Inst Pharmacol & Toxicol, Zurich, Switzerland
[2] ETH, Inst Pharmaceut Sci, Swiss Fed Inst Technol, Zurich, Switzerland
[3] Heidelberg Univ, Dept Anesthesiol Mannheim, Heidelberg, Germany
关键词
INTRAVENOUS LIDOCAINE; PAIN; HYPERALGESIA; INHIBITORS; GABA(A);
D O I
10.1097/j.pain.0000000000000233
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
引用
收藏
页码:1579 / 1580
页数:2
相关论文
共 20 条
[1]   Systemic lidocaine in pain due to peripheral nerve injury and predictors of response [J].
Attal, N ;
Rouaud, J ;
Brasseur, L ;
Chauvin, M ;
Bouhassira, D .
NEUROLOGY, 2004, 62 (02) :218-225
[2]   Intravenous lidocaine in central pain -: A double-blind, placebo-controlled, psychophysical study [J].
Attal, N ;
Gaudé, V ;
Brasseur, L ;
Dupuy, M ;
Guirimand, F ;
Parker, F ;
Bouhassira, D .
NEUROLOGY, 2000, 54 (03) :564-574
[3]   The time course of transmitter at glycinergic synapses onto motoneurons [J].
Beato, Marco .
JOURNAL OF NEUROSCIENCE, 2008, 28 (29) :7412-7425
[4]   Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain [J].
Dohi, Toshihiro ;
Morita, Katsuya ;
Kitayama, Tomoya ;
Motoyama, Naoyo ;
Morioka, Norimitsu .
PHARMACOLOGY & THERAPEUTICS, 2009, 123 (01) :54-79
[5]   Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch [J].
Foster, Edmund ;
Wildner, Hendrik ;
Tudeau, Laetitia ;
Haueter, Sabine ;
Ralvenius, William T. ;
Jegen, Monika ;
Johannssen, Helge ;
Hoesli, Ladina ;
Haenraets, Karen ;
Ghanem, Alexander ;
Conzelmann, Karl-Klaus ;
Boesl, Michael ;
Zeilhofer, Hanns Ulrich .
NEURON, 2015, 85 (06) :1289-1304
[6]   TREATMENT OF CHRONIC PAINFUL DIABETIC NEUROPATHY WITH INTRAVENOUS LIDOCAINE INFUSION [J].
KASTRUP, J ;
ANGELO, HR ;
PETERSEN, P ;
DEJGARD, A ;
HILSTED, J .
BRITISH MEDICAL JOURNAL, 1986, 292 (6514) :173-173
[7]   Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans [J].
Koppert, W ;
Zeck, S ;
Sittl, R ;
Likar, R ;
Knoll, R ;
Schmelz, M .
ANESTHESIOLOGY, 1998, 89 (06) :1345-1353
[8]   Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action [J].
Koppert, W ;
Ostermeier, N ;
Sittl, R ;
Weidner, C ;
Schmelz, M .
PAIN, 2000, 85 (1-2) :217-224
[9]   THE ANALGESIC EFFECT OF TOCAINIDE IN TRIGEMINAL NEURALGIA [J].
LINDSTROM, P ;
LINDBLOM, U .
PAIN, 1987, 28 (01) :45-50
[10]   GABAA and glycine receptor-mediated transmission in rat lamina II neurones:: relevance to the analgesic actions of neuroactive steroids [J].
Mitchell, Elizabeth A. ;
Gentet, Luc J. ;
Dempster, John ;
Belellil, Delia .
JOURNAL OF PHYSIOLOGY-LONDON, 2007, 583 (03) :1021-1040