Measurement of breast-tissue x-ray attenuation by spectral mammography: First results on cyst fluid

被引：1

作者：

Fredenberg, Erik ^{[1
]}

Dance, David R. ^{[2
,3
]}

Willsher, Paula ^{[4
,5
]}

von Tiedemann, Miriam ^{[1
]}

Young, Kenneth C. ^{[2
,3
]}

Wallis, Matthew G. ^{[4
,5
]}

机构：

[1] Philips Mammog Solut, Smidesvagen 5, S-17141 Solna, Sweden

[2] NCCPM, Royal Surrey Cty Hosp, Guildford GU2 7XX, Surrey, England

[3] Univ Surrey, Dept Phys, Guildford GU2 7XX, Surrey, England

[4] Addenbrookes Hosp, NIHR, Cambridge Biomed Res Ctr, Cambridge CB2 0QQ, England

[5] Addenbrookes Hosp, Cambridge Breast Unit, Cambridge CB2 0QQ, England

来源：

MEDICAL IMAGING 2013: PHYSICS OF MEDICAL IMAGING | 2013年 / 8668卷

基金：

英国工程与自然科学研究理事会;

关键词：

mammography; spectral imaging; x-ray attenuation; cyst; DIGITAL MAMMOGRAPHY; ENERGY; TOMOGRAPHY; DETECTOR;

D O I：

10.1117/12.2008026

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. For instance, techniques to better characterize cysts at mammography screening would be highly desirable to reduce recalls, but the development is hampered by the lack of attenuation data for cysts. We have developed a method to measure x-ray attenuation of tissue samples using a prototype photon-counting spectral mammography unit. Spectral (energy-resolved) images were acquired and the image signal was mapped to two known reference materials, which were used to derive the x-ray attenuation as a function of energy. We have measured the attenuation of 25 samples of breast cyst fluid. Spectral measurements of water samples showed consistent results compared to published attenuation values.

引用

页数：7

共 19 条

[1] ENERGY-SELECTIVE RECONSTRUCTIONS IN X-RAY COMPUTERIZED TOMOGRAPHY [J].

ALVAREZ, RE ;

MACOVSKI, A .

PHYSICS IN MEDICINE AND BIOLOGY, 1976, 21 (05) :733-744

[2] Scatter rejection in multislit digital mammography [J].

Åslund, M ;

Cederström, B ;

Lundqvist, M ;

Danielsson, M .

MEDICAL PHYSICS, 2006, 33 (04) :933-940

[3]

Berger M J., 1999, XCOM: photon cross sections database

[4] Molybdenum, rhodium, and tungsten anode spectral models using interpolating polynomials with application to mammography [J].

Boone, JM ;

Fewell, TR ;

Jennings, RJ .

MEDICAL PHYSICS, 1997, 24 (12) :1863-1874

[5] Detective quantum efficiency dependence on x-ray energy weighting in mammography [J].

Cahn, RN ;

Cederström, B ;

Danielsson, M ;

Hall, A ;

Lundqvist, M ;

Nygren, D .

MEDICAL PHYSICS, 1999, 26 (12) :2680-2683

[6] ATTENUATION OF MONOCHROMATIC X-RAYS BY NORMAL AND ABNORMAL BREAST TISSUES [J].

CARROLL, FE ;

WATERS, JW ;

ANDREWS, WW ;

PRICE, RR ;

PICKENS, DR ;

WILLCOTT, R ;

TOMPKINS, P ;

ROOS, C ;

PAGE, D ;

REED, G ;

UEDA, A ;

BAIN, R ;

WANG, P ;

BASSINGER, M .

INVESTIGATIVE RADIOLOGY, 1994, 29 (03) :266-272

[7] Measurement of the linear attenuation coefficients of breast tissues by synchrotron radiation computed tomography [J].

Chen, R. C. ;

Longo, R. ;

Rigon, L. ;

Zanconati, F. ;

De Pellegrin, A. ;

Arfelli, F. ;

Dreossi, D. ;

Menk, R-H ;

Vallazza, E. ;

Xiao, T. Q. ;

Castelli, E. .

PHYSICS IN MEDICINE AND BIOLOGY, 2010, 55 (17) :4993-5005

[8] Quantification of breast density with spectral mammography based on a scanned multi-slit photon-counting detector: a feasibility study [J].

Ding, Huanjun ;

Molloi, Sabee .

PHYSICS IN MEDICINE AND BIOLOGY, 2012, 57 (15) :4719-4738

[9]

Fredenberg E., 2010, P SPIE MED IM 2010 P

[10] Energy resolution of a photon-counting silicon strip detector [J].

Fredenberg, Erik ;

Lundqvist, Mats ;

Cederstrom, Bjorn ;

Aslund, Magnus ;

Danielsson, Mats .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2010, 613 (01) :156-162

← 1 2 →