Prebiotics and their long-term influence on the microbial populations of the mouse bowel

被引:57
作者
Santos, A [1 ]
San Mauro, M [1 ]
Díaz, DM [1 ]
机构
[1] Univ Complutense Madrid, Fac Biol, Dept Microbiol 3, E-28040 Madrid, Spain
关键词
prebiotics; mice; microbial populations; small bowel; large bowel;
D O I
10.1016/j.fm.2005.07.004
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Various prebiotics were orally administered to mice and the evolution of different microbial populations was studied. The administration of prebiotics significantly increased lactobacilli and bifidobacteria in the large bowel content. Ingestion of prebiotics specifically lowered microbial populations of sulphite-reducing clostridia. Xylo-oligosaccharides (XOS) increased lactobacilli by 10 fold and produced the highest counts of bifidobacteria. In XOS-treated mice, levels of sulphite-reducing clostridia decreased significantly. Prebiotics slightly reduced the amount of aerobic bacteria and significantly increased the number of anaerobes in both the small and the large bowel. These effects of prebiotics were reverted by the basal diet. ((c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:498 / 503
页数:6
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