Use and Abuse of RNAi to Study Mammalian Gene Function

被引:125
作者
Kaelin, William G., Jr. [1 ]
机构
[1] Dana Farber Canc Inst, Dept Adult Oncol, Off M457, Boston, MA 02215 USA
关键词
HUMAN-CELLS; SCREENS; INTERFERENCE; EXPRESSION;
D O I
10.1126/science.1225787
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Realizing the full potential of si/shRNA technology requires more sophisticated approaches to address the pitfalls.
引用
收藏
页码:421 / 422
页数:2
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