Male Fertility After Cancer

被引：49
作者：
Sabanegh, Edmund S., Jr. [1 ]
Ragheb, Ahmed M. [1 ]
机构：
[1] Cleveland Clin Fdn, Glickman Urol & Kidney Inst, Cleveland, OH 44195 USA
来源：
UROLOGY | 2009年 / 73卷 / 02期
关键词：
TESTICULAR CANCER; HODGKINS-DISEASE; GONADAL-FUNCTION; MALE-INFERTILITY; SPARING SURGERY; SEMEN QUALITY; CHEMOTHERAPY; SPERM; MEN; CRYOPRESERVATION;
D O I：
10.1016/j.urology.2008.08.474
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The increasing incidence of cancer among the reproductive population, especially Hodgkin's disease (HD) and testicular cancer, has been paralleled by a substantial improvement in survival rates. In addition to survival and recurrence rates, preserving future fertility and subsequent offspring welfare have become a main focus of modern treatment modalities and current extensive research. This article reviews contemporary data on the effects of cancer and cancer treatment on mate fecundity. Gonadotoxicity of cytotoxic therapy will be discussed together with the current measures to preserve fertility. Finally, recent data on potential harm to future offspring of cancer survivors will be addressed. UROLOGY 73: 225-231, 2009. (C) 2009 Published by Elsevier Inc.
引用
收藏
页码：225 / 231
页数：7
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