RNA interference in Colorado potato beetle: steps toward development of dsRNA as a commercial insecticide

被引:140
作者
Palli, Subba Reddy [1 ]
机构
[1] Univ Kentucky, Dept Entomol, Coll Agr, Lexington, KY 40546 USA
关键词
DOUBLE-STRANDED-RNA; LEPTINOTARSA-DECEMLINEATA SAY; PLANT-MEDIATED RNAI; DESERT LOCUST; PERMETHRIN CARBOXYLESTERASE; NEONICOTINOID INSECTICIDES; AZINPHOSMETHYL RESISTANCE; GENETIC INTERFERENCE; POPULATION-DYNAMICS; PIPERONYL BUTOXIDE;
D O I
10.1016/j.cois.2014.09.011
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Colorado potato beetle (CPB) is a notorious pest on potatoes and has a remarkable ability to detoxify plant chemicals and develop resistance against insecticides. dsRNA targeting CPB genes could be expressed in potato plants to control this pest. However, previous attempts at introducing transgenic potato plants to control CPB were not highly successful. Recent studies showed that feeding dsRNA expressed in bacteria works very well to kill CPB. To realize the potential of RNAi to control this and other economically important pests, more efficient methods for production and delivery of dsRNA need to be developed. Extensive research to determine off-target and non-target effects, environmental fate and potential for resistance development is also essential.
引用
收藏
页码:1 / 8
页数:8
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