Case 18-2013: A 32-Year-Old Woman with Recurrent Episodes of Altered Consciousness Oligoastrocytoma, WHO grade II of IV, associated with temporal-lobe seizures and ictal asystole (arrhythmogenic epilepsy)

被引：3

作者：

Cole, Andrew J. ^{[1
,6
]}

Eskandar, Emad ^{[2
,7
]}

Mela, Theofanie ^{[3
,8
]}

Noebels, Jeffrey L. ^{[11
]}

Gonzalez, R. Gilberto ^{[4
,9
]}

McGuone, Declan ^{[5
,10
]}

机构：

[1] Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA

[5] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

[6] Harvard Univ, Sch Med, Dept Neurol, Boston, MA 02115 USA

[7] Harvard Univ, Sch Med, Dept Neurosurg, Boston, MA 02115 USA

[8] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA

[9] Harvard Univ, Sch Med, Dept Radiol, Boston, MA 02115 USA

[10] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[11] Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2013年 / 368卷 / 24期

关键词：

LONG-QT SYNDROME; BRADYCARDIA; IDENTIFICATION; LOBECTOMY; GENETICS; SYNCOPE; DEATH;

D O I：

10.1056/NEJMcpc1215969

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2304 / 2312

页数：9

共 32 条

[1] Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4 [J].

Baruscotti, Mirko ;

Bucchi, Annalisa ;

Viscomi, Carlo ;

Mandelli, Giacomo ;

Consalez, Giacomo ;

Gnecchi-Rusconi, Tomaso ;

Montano, Nicola ;

Casali, Karina Rabello ;

Micheloni, Stefano ;

Barbuti, Andrea ;

DiFrancesco, Dario .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (04) :1705-1710

[2] The ictal bradycardia syndrome: Localization and lateralization [J].

Britton, JW ;

Ghearing, GR ;

Benarroch, EE ;

Cascino, GD .

EPILEPSIA, 2006, 47 (04) :737-744

[3] Genetics of sudden death: focus on inherited channelopathies [J].

Cerrone, Marina ;

Priori, Silvia G. .

EUROPEAN HEART JOURNAL, 2011, 32 (17) :2109-U148

[4] Recessive Loss-of-Function Mutation in the Pacemaker HCN2 Channel Causing Increased Neuronal Excitability in a Patient with Idiopathic Generalized Epilepsy [J].

DiFrancesco, Jacopo C. ;

Barbuti, Andrea ;

Milanesi, Raffaella ;

Coco, Stefania ;

Bucchi, Annalisa ;

Bottelli, Georgia ;

Ferrarese, Carlo ;

Franceschetti, Silvana ;

Terragni, Benedetta ;

Baruscotti, Mirko ;

DiFrancesco, Dario .

JOURNAL OF NEUROSCIENCE, 2011, 31 (48) :17327-17337

[5] Seizure outcome after temporal lobectomy for temporal lobe epilepsy - A Kaplan-Meier survival analysis [J].

Foldvary, N ;

Nashold, B ;

Mascha, E ;

Thompson, EA ;

Lee, N ;

McNamara, JO ;

Lewis, DV ;

Luther, JS ;

Friedman, AH ;

Radtke, RA .

NEUROLOGY, 2000, 54 (03) :630-634

[6] Kv1.1 Potassium Channel Deficiency Reveals Brain-Driven Cardiac Dysfunction as a Candidate Mechanism for Sudden Unexplained Death in Epilepsy [J].

Glasscock, Edward ;

Yoo, Jong W. ;

Chen, Tim T. ;

Klassen, Tara L. ;

Noebels, Jeffrey L. .

JOURNAL OF NEUROSCIENCE, 2010, 30 (15) :5167-5175

[7] Arrhythmia in Heart and Brain: KCNQ1 Mutations Link Epilepsy and Sudden Unexplained Death [J].

Goldman, A. M. ;

Glasscock, E. ;

Yoo, J. ;

Chen, T. T. ;

Klassen, T. L. ;

Noebels, J. L. .

SCIENCE TRANSLATIONAL MEDICINE, 2009, 1 (02)

[8] Interictal-like network activity and receptor expression in the epileptic human lateral amygdala [J].

Graebenitz, Stephanie ;

Kedo, Olga ;

Speckmann, Erwin-Josef ;

Gorji, Ali ;

Panneck, Heinz ;

Hans, Volkmar ;

Palomero-Gallagher, Nicola ;

Schleicher, Axel ;

Zilles, Karl ;

Pape, Hans-Christian .

BRAIN, 2011, 134 :2929-2947

[9] Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy [J].

Johnson, J. N. ;

Hofman, N. ;

Haglund, C. M. ;

Cascino, G. D. ;

Wilde, A. A. M. ;

Ackerman, M. J. .

NEUROLOGY, 2009, 72 (03) :224-231

[10] Use of Mutant-Specific Ion Channel Characteristics for Risk Stratification of Long QT Syndrome Patients [J].

Jons, Christian ;

O-Uchi, Jin ;

Moss, Arthur J. ;

Reumann, Matthias ;

Rice, John J. ;

Goldenberg, Ilan ;

Zareba, Wojciech ;

Wilde, Arthur A. M. ;

Shimizu, Wataru ;

Kanters, Jorgen K. ;

McNitt, Scott ;

Hofman, Nynke ;

Robinson, Jennifer L. ;

Lopes, Coeli M. B. .

SCIENCE TRANSLATIONAL MEDICINE, 2011, 3 (76)

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