TBD-Catalyzed Trifluoromethylation of Carbonyl Compounds with (Trifluoromethyl)trimethylsilane

被引：12

作者：

Matsukawa, S. ^{[1
]}

Takahashi, S. ^{[1
]}

Takahashi, H. ^{[1
]}

机构：

[1] Ibaraki Univ, Fac Educ, Dept Sci Educ, Mito, Ibaraki 3108512, Japan

来源：

SYNTHETIC COMMUNICATIONS | 2013年 / 43卷 / 11期

关键词：

Base catalyst; guanidine; organocatalyst; organosilicon compounds; trifluoromethylation; TRIALKYL(TRIFLUOROMETHYL)SILANES;

D O I：

10.1080/00397911.2011.644381

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trifluoromethylation of carbonyl compounds using (trifluoromethyl) trimethylsilane catalyzed by 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding -trifluoromethyl alcohols in good to excellent yields under mild reaction conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.

引用

页码：1523 / 1529

页数：7