Neutropenia and Thrombocytopenia Induced By Quetiapine Monotherapy: A Case Report and Review of Literature

被引：10

作者：

Arslan, Filiz Civil ^{[1
]}

Aykut, Demet Saglam ^{[1
]}

Ince, Canan ^{[1
]}

Tiryaki, Ahmet ^{[1
]}

机构：

[1] Karadeniz Tech Univ, Sch Med, Dept Psychiat, Kalkinma Mahallesi, TR-61080 Trabzon, Turkey

来源：

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY | 2016年 / 26卷 / 03期

关键词：

Quetiapine; neutropenia; thrombocytopenia; INDUCED LEUKOPENIA; VALPROATE; PATIENT; GRANULOCYTOPENIA; COMEDICATION; CLOZAPINE; XR;

D O I：

10.5455/bcp.20151219072235

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Antipsychotic drugs can cause neutropenia which can progress to life-threatening agranulocytosis. Clozapine is well-known for this side effect which is rare for other antipsychotics. Quetiapine is a newer atypical antipsychotic which shows similarities with clozapine in chemical structure. We present a rare case of neutropenia and thrombocytopenia induced by quetiapine monotherapy of 600 mg/day in a 69-year old patient with the diagnosis of bipolar I disorder. Hematological adverse effects were resolved by the discontinuation of quetiapine treatment. Although monitoring blood counts during quetiapine use is not recommended, clinicians should be aware of this rare but hazardous side effect.

引用

页码：319 / 323

页数：5

共 25 条

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