Biomedical applications of a real-time terahertz color scanner

被引：50

作者：

Schirmer, Markus ^{[1
]}

Fujio, Makoto ^{[1
]}

Minami, Masaaki ^{[1
]}

Miura, Jiro ^{[2
]}

Araki, Tsutomu ^{[1
]}

Yasui, Takeshi ^{[1
,3
]}

机构：

[1] Osaka Univ, Grad Sch Engn Sci, Toyonaka, Osaka 5608531, Japan

[2] Osaka Univ Dent Hosp, Div Interdisciplinary Dent, Suita, Osaka 5650871, Japan

[3] Univ Tokushima, Inst Sci & Technol, Tokushima 7708506, Japan

来源：

BIOMEDICAL OPTICS EXPRESS | 2010年 / 1卷 / 02期

关键词：

Medical applications - Scanning - Inspection - Spectroscopy - Color;

D O I：

10.1364/BOE.1.000354

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A real-time THz color scanner has the potential to further expand the application scope of THz spectral imaging based on its rapid image acquisition rate. We demonstrated three possible applications of a THz color scanner in the biomedical field: imaging of pharmaceutical tablets, human teeth, and human hair. The first application showed the scanner's potential in total inspection for rapid quality control of pharmaceutical tablets moving on a conveyor belt. The second application demonstrated that the scanner can be used to identify a potential indicator for crystallinity of dental tissue. In the third application, the scanner was successfully used to visualize the drying process of wet hairs. These demonstrations indicated the high potential of the THz color scanner for practical applications in the biomedical field. (C) 2010 Optical Society of America

引用

页码：354 / 366

页数：13

共 23 条

[1] Diagnosing water content in paper by terahertz radiation [J].

Banerjee, D. ;

von Spiegel, W. ;

Thomson, M. D. ;

Schabel, S. ;

Roskos, H. G. .

OPTICS EXPRESS, 2008, 16 (12) :9060-9066

[2] Three-dimensional terahertz pulse imaging of dental tissue [J].

Crawley, D ;

Longbottom, C ;

Wallace, VP ;

Cole, B ;

Arnone, D ;

Pepper, M .

JOURNAL OF BIOMEDICAL OPTICS, 2003, 8 (02) :303-307

[3] Terahertz spectroscopy for art conservation [J].

Fukunaga, Kaori ;

Ogawa, Yuichi ;

Hayashi, Shin'ichiro ;

Hosako, Iwao .

IEICE ELECTRONICS EXPRESS, 2007, 4 (08) :258-263

[4] Terahertz pulsed imaging of frozen biological tissues [J].

Hoshina, Hiromichi ;

Hayashi, Aya ;

Miyoshi, Norio ;

Miyamaru, Fumiaki ;

Otani, Chiko .

APPLIED PHYSICS LETTERS, 2009, 94 (12)

[5] Non-destructive terahertz imaging of illicit drugs using spectral fingerprints [J].

Kawase, K ;

Ogawa, Y ;

Watanabe, Y ;

Inoue, H .

OPTICS EXPRESS, 2003, 11 (20) :2549-2554

[6] Far-infrared dielectric properties of polar liquids probed by femtosecond terahertz pulse spectroscopy [J].

Kindt, JT ;

Schmuttenmaer, CA .

JOURNAL OF PHYSICAL CHEMISTRY, 1996, 100 (24) :10373-10379

[7] Terahertz dark-field imaging of biomedical tissue [J].

Löffler, T ;

Bauer, T ;

Siebert, KJ ;

Roskos, HG ;

Fitzgerald, A ;

Czasch, S .

OPTICS EXPRESS, 2001, 9 (12) :616-621

[8] Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz [J].

Markelz, AG ;

Roitberg, A ;

Heilweil, EJ .

CHEMICAL PHYSICS LETTERS, 2000, 320 (1-2) :42-48

[9] T-ray imaging [J].

Mittleman, DM ;

Jacobsen, RH ;

Nuss, MC .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1996, 2 (03) :679-692

[10] Terahertz two-dimensional electrooptic sampling using high speed complementary metal-oxide semiconductor camera [J].

Miyamaru, F ;

Yonera, T ;

Tani, M ;

Hangyo, M .

JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS & EXPRESS LETTERS, 2004, 43 (4A) :L489-L491

← 1 2 3 →