Mighty small: Observing and modeling individual microbes becomes big science

被引：47

作者：

Kreft, Jan-Ulrich ^{[1
]}

Plugge, Caroline M. ^{[2
]}

Grimm, Volker ^{[3
,4
,5
]}

Prats, Clara ^{[6
]}

Leveau, Johan H. J. ^{[7
]}

Banitz, Thomas ^{[3
]}

Baines, Stephen ^{[8
]}

Clark, James ^{[9
]}

Ros, Alexandra ^{[10
]}

Klapper, Isaac ^{[11
]}

Topping, Chris J. ^{[12
]}

Field, Anthony J. ^{[13
]}

Schuler, Andrew ^{[14
]}

Litchman, Elena ^{[15
]}

Hellweger, Ferdi L. ^{[16
]}

机构：

[1] Univ Birmingham, Sch Biosci, Ctr Syst Biol, Birmingham B15 2TT, W Midlands, England

[2] Wageningen Univ, Dept Agrotechnol & Food Sci, Microbiol Lab, NL-6703 HB Wageningen, Netherlands

[3] UFZ Helmholtz Ctr Environm Res, Dept Ecol Modelling, D-04318 Leipzig, Germany

[4] Univ Potsdam, Inst Biochem & Biol, D-14469 Potsdam, Germany

[5] German Ctr Integrat Biodivers Res iDiv, D-04103 Leipzig, Germany

[6] Univ Politecn Catalunya BarcelonaTech, Sch Agr Engn Barcelona, Dept Phys & Nucl Engn, Castelldefels 08860, Spain

[7] Univ Calif Davis, Dept Plant Pathol, Davis, CA 95616 USA

[8] SUNY Stony Brook, Dept Ecol & Evolut, Stony Brook, NY 11794 USA

[9] Plymouth Marine Lab, Plymouth PL1 3DH, Devon, England

[10] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

[11] Temple Univ, Dept Math, Philadelphia, PA 19122 USA

[12] Aarhus Univ, Dept Biosci, DK-8410 Ronde, Denmark

[13] Univ London Imperial Coll Sci Technol & Med, Dept Comp, London SW7 2AZ, England

[14] Univ New Mexico, Dept Civil Engn, Albuquerque, NM 87106 USA

[15] Michigan State Univ, Kellogg Biol Stn, Hickory Corners, MI 49060 USA

[16] Northeastern Univ, Dept Civil & Environm Engn, Boston, MA 02115 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2013年 / 110卷 / 45期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1073/pnas.1317472110

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：18027 / 18028

页数：2

共 6 条

[1] Microscale patchiness leads to large and important intraspecific internal nutrient heterogeneity in phytoplankton [J].

Bucci, Vanni ;

Nunez-Milland, Daliangelis ;

Twining, Benjamin S. ;

Hellweger, Ferdi L. .

AQUATIC ECOLOGY, 2012, 46 (01) :101-118

[2] Pattern-oriented modeling of agent-based complex systems: Lessons from ecology [J].

Grimm, V ;

Revilla, E ;

Berger, U ;

Jeltsch, F ;

Mooij, WM ;

Railsback, SF ;

Thulke, HH ;

Weiner, J ;

Wiegand, T ;

DeAngelis, DL .

SCIENCE, 2005, 310 (5750) :987-991

[3] iDynoMiCS: next-generation individual-based modelling of biofilms [J].

Lardon, Laurent A. ;

Merkey, Brian V. ;

Martins, Sonia ;

Doetsch, Andreas ;

Picioreanu, Cristian ;

Kreft, Jan-Ulrich ;

Smets, Barth F. .

ENVIRONMENTAL MICROBIOLOGY, 2011, 13 (09) :2416-2434

[4] Detecting metabolic activities in single cells, with emphasis on nanoSIMS [J].

Musat, Niculina ;

Foster, Rachel ;

Vagner, Tomas ;

Adam, Birgit ;

Kuypers, Marcel M. M. .

FEMS MICROBIOLOGY REVIEWS, 2012, 36 (02) :486-511

[5] Computational Modeling of Synthetic Microbial Biofilms [J].

Rudge, Timothy J. ;

Steiner, Paul J. ;

Phillips, Andrew ;

Haseloff, Jim .

ACS SYNTHETIC BIOLOGY, 2012, 1 (08) :345-352

[6] Going local: technologies for exploring bacterial microenvironments [J].

Wessel, Aimee K. ;

Hmelo, Laura ;

Parsek, Matthew R. ;

Whiteley, Marvin .

NATURE REVIEWS MICROBIOLOGY, 2013, 11 (05) :337-348

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