Room temperature decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids by photoredox catalysis

被引：122

作者：

Xu, Pan ^{[1
]}

Abdukader, Ablimit ^{[1
]}

Hu, Kaidong ^{[1
]}

Cheng, Yixiang ^{[1
]}

Zhu, Chengjian ^{[1
,2
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 18期

基金：

中国国家自然科学基金; 高等学校博士学科点专项科研基金;

关键词：

BOND FORMATION; LIGHT; ARENES; ARYL; FUNCTIONALIZATION; FLUORINE; ALKENES; CASCADE;

D O I：

10.1039/c3cc48598f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A visible-light-induced decarboxylative trifluoromethylation of alpha,beta-unsaturated carboxylic acids, which uses the Togni reagent as the CF3 source is disclosed. The corresponding trifluoromethylated alkenes were obtained in moderate to high yields with excellent functional group tolerance at ambient temperature. Preliminary mechanistic analyses suggest a radical-type mechanism.

引用

页码：2308 / 2310

页数：3

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