Evolution of cortical neurons supporting human cognition

被引：56

作者：

Galakhova, A. A. ^{[1
]}

Hunt, S. ^{[1
]}

Wilbers, R. ^{[1
]}

Heyer, D. B. ^{[1
]}

de Kock, C. P. J. ^{[1
]}

Mansvelder, H. D. ^{[1
]}

Goriounova, N. A. ^{[1
]}

机构：

[1] Vrije Univ Amsterdam, Ctr Neurogen & Cognit Res CNCR, Dept Integrat Neurosci, Boelelaan 1085, NL-1081 HV Amsterdam, Netherlands

来源：

TRENDS IN COGNITIVE SCIENCES | 2022年 / 26卷 / 11期

基金：

荷兰研究理事会;

关键词：

LATERAL TEMPORAL CORTEX; PYRAMIDAL NEURONS; PREFRONTAL CORTEX; HUMAN BRAIN; ACTION-POTENTIALS; MOTOR CORTEX; GREAT APES; P-FIT; INTELLIGENCE; THICKNESS;

D O I：

10.1016/j.tics.2022.08.012

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Human cognitive abilities are generally thought to arise from cortical expansion over the course of human brain evolution. In addition to increased neuron numbers, this cortical expansion might be driven by adaptations in the properties of single neurons and their local circuits. We review recent findings on the distinct structural, functional, and transcriptomic features of human cortical neurons and their organi-zation in cortical microstructure. We focus on the supragranular cortical layers, which showed the most prominent expansion during human brain evolution, and the properties of their principal cells: pyramidal neurons. We argue that the evolu-tionary adaptations in neuronal features that accompany the expansion of the human cortex partially underlie interindividual variability in human cognitive abilities.

引用

页码：909 / 922

页数：14

共 107 条

[81] Lifespan alterations of basal dendritic trees of pyramidal neurons in the human prefrontal cortex: A layer-specific pattern [J].