An independent, landmark-dominated head-direction signal in dysgranular retrosplenial cortex

被引:146
作者
Jacobs, Pierre-Yves [1 ]
Casali, Giulio [1 ]
Spieser, Laure [2 ]
Page, Hector [1 ]
Overington, Dorothy [1 ]
Jeffery, Kate [1 ]
机构
[1] UCL, Inst Behav Neurosci, Div Psychol & Language Sci, Res Dept Expt Psychol, London, England
[2] City Univ London, Dept Psychol, London, England
基金
英国医学研究理事会; 英国惠康基金; 英国生物技术与生命科学研究理事会;
关键词
RAT POSTERIOR CORTEX; PLACE CELLS; MEMORY;
D O I
10.1038/nn.4465
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We investigated how landmarks influence the brain's computation of head direction and found that in a bidirectionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bidirectional firing patterns. This indicates dominance of neural activity by local environmental cues even when these conflicted with the global head direction signal. It suggests a mechanism for associating landmarks to or dissociating them from the head direction signal, according to their directional stability and/or utility.
引用
收藏
页码:173 / 175
页数:3
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