Immunotherapy in Nonmelanoma Skin Cancer

被引：5

作者：

Bassas Freixas, P. ^{[1
]}

Aparicio Espanol, G. ^{[1
]}

Garcia-Patos Briones, V ^{[1
]}

机构：

[1] Hosp Univ Vail dHebron, Serv Dermatol, Barcelona, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2019年 / 110卷 / 05期

关键词：

Nonmelanoma skin cancer; Immunotherapy; Programmed cell death protein 1 (PD-1); Programmed death ligand 1 (PD-L1); Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4); SQUAMOUS-CELL CARCINOMA; LONG-TERM SURVIVAL; DEATH LIGAND; IPILIMUMAB; EXPRESSION; PEMBROLIZUMAB; REGRESSION; BLOCKADE; CTLA-4; PD-L2;

D O I：

10.1016/j.ad.2018.09.013

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Immunotherapy is emerging as a new and promising treatment for a great variety of tumors, including nonmelanoma skin cancer. Checkpoint inhibitors - antibodies that block proteins that regulate the immune system - mainly target the surface protein CTLA-4 (cytotoxic T-lymphocyte-associated antigen 4) and the PD-1/PD-L1 (programmed cell death protein 1/PD-ligand 1) axis. We review the CTLA-4 and PD-1/PD-L1 pathways and current evidence supporting checkpoint inhibitor therapy in the main types of nonmelanoma skin cancer. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：353 / 359

页数：7

共 50 条

[41] Cancer mortality after nonmelanoma skin cancer
Spratt, JS
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 281 (04): : 325 - 325
[42] Nonmelanoma skin cancer arising on tattoos
Rubatto, Marco
Gelato, Federica
Mastorino, Luca
Giordano, Silvia
Ribero, Simone
Quaglino, Pietro
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2023, 62 (03) : E155 - E156
[43] Commentary: The incidence of nonmelanoma skin cancer
Rigel, Darrell S.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2014, 71 (01) : 27 - 28
[44] Advanced and recurrent nonmelanoma skin cancer
Luce, EA
CLINICS IN PLASTIC SURGERY, 1997, 24 (04) : 731 - &
[45] PROGNOSIS IN NONMELANOMA SKIN-CANCER
SUAREZVARELA, MMM
GONZALEZ, AL
CARACO, EF
REVISTA CLINICA ESPANOLA, 1992, 191 (03): : 171 - 172
[46] INCIDENCE OF NONMELANOMA SKIN-CANCER
URBACH, F
DERMATOLOGIC CLINICS, 1991, 9 (04) : 751 - 755
[47] Lasers in the Treatment of Nonmelanoma Skin Cancer
Choudhary, Sonal
Tang, Jennifer
Elsaie, Mohamed L.
Nouri, Keyvan
DERMATOLOGIC SURGERY, 2011, 37 (04) : 409 - 425
[48] Nonmelanoma Skin Cancer Part 2
Nolen, Mary E.
Beebe, Victoria R.
King, Jeanne M.
Bryn, Niki
Limaye, Karen Morin
JOURNAL OF THE DERMATOLOGY NURSES ASSOCIATION, 2011, 3 (06) : 326 - 341
[49] Nonsurgical Treatment of Nonmelanoma Skin Cancer
Galiczynski, Edward M.
Vidimos, Allison T.
DERMATOLOGIC CLINICS, 2011, 29 (02) : 297 - +
[50] DNA ploidy in nonmelanoma skin cancer
Robinson, JK
Rademaker, AW
Goolsby, C
Traczyk, TN
Zoladz, C
CANCER, 1996, 77 (02) : 284 - 291

← 1 2 3 4 5 →