Immunotherapy in Nonmelanoma Skin Cancer

被引：5
|
作者：
Bassas Freixas, P. [1 ]
Aparicio Espanol, G. [1 ]
Garcia-Patos Briones, V [1 ]
机构：
[1] Hosp Univ Vail dHebron, Serv Dermatol, Barcelona, Spain
来源：
ACTAS DERMO-SIFILIOGRAFICAS | 2019年 / 110卷 / 05期
关键词：
Nonmelanoma skin cancer; Immunotherapy; Programmed cell death protein 1 (PD-1); Programmed death ligand 1 (PD-L1); Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4); SQUAMOUS-CELL CARCINOMA; LONG-TERM SURVIVAL; DEATH LIGAND; IPILIMUMAB; EXPRESSION; PEMBROLIZUMAB; REGRESSION; BLOCKADE; CTLA-4; PD-L2;
D O I：
10.1016/j.ad.2018.09.013
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Immunotherapy is emerging as a new and promising treatment for a great variety of tumors, including nonmelanoma skin cancer. Checkpoint inhibitors - antibodies that block proteins that regulate the immune system - mainly target the surface protein CTLA-4 (cytotoxic T-lymphocyte-associated antigen 4) and the PD-1/PD-L1 (programmed cell death protein 1/PD-ligand 1) axis. We review the CTLA-4 and PD-1/PD-L1 pathways and current evidence supporting checkpoint inhibitor therapy in the main types of nonmelanoma skin cancer. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码：353 / 359
页数：7
相关论文
共 50 条
  • [11] Immunotherapy for Non-melanoma Skin Cancer
    Shalhout, Sophia Z.
    Emerick, Kevin S.
    Kaufman, Howard L.
    Miller, David M.
    CURRENT ONCOLOGY REPORTS, 2021, 23 (11)
  • [12] Chemoprevention of Nonmelanoma Skin Cancer
    Soltani-Arabshahi, Razieh
    Tristani-Firouzi, Payam
    FACIAL PLASTIC SURGERY, 2013, 29 (05) : 373 - 383
  • [13] Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer
    Shou-En Wu
    Yi-Hsien Chen
    Chih-Tsung Hung
    Bing-Heng Yang
    Current Treatment Options in Oncology, 2023, 24 : 496 - 514
  • [14] Radiotherapy treatment for nonmelanoma skin cancer
    Rong, Yi
    Zuo, Li
    Shang, Lu
    Bazan, Jose G.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2015, 15 (07) : 765 - 776
  • [15] Immunotherapy for Non-melanoma Skin Cancer
    Sophia Z. Shalhout
    Kevin S. Emerick
    Howard L. Kaufman
    David M. Miller
    Current Oncology Reports, 2021, 23
  • [16] Rapid visualization of nonmelanoma skin cancer
    Walker, Ethan
    Mann, Margaret
    Honda, Kord
    Vidimos, Allison
    Schluchter, Mark D.
    Straight, Brian
    Bogyo, Matthew
    Popkin, Daniel
    Basilion, James P.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (02) : 209 - +
  • [17] Cognitive Adaptation to Nonmelanoma Skin Cancer
    Czajkowska, Zofia
    Radiotis, George
    Roberts, Nicole
    Koerner, Annett
    JOURNAL OF PSYCHOSOCIAL ONCOLOGY, 2013, 31 (04) : 377 - 392
  • [18] Quality of Life in Nonmelanoma Skin Cancer
    Garcia-Montero, P.
    de Galvez-Aranda, M. V.
    de Troya Martin, M.
    ACTAS DERMO-SIFILIOGRAFICAS, 2018, 109 (07): : 649 - 650
  • [19] Novel approaches for managing aged skin and nonmelanoma skin cancer
    Todorova, Kristina
    Mandinova, Anna
    ADVANCED DRUG DELIVERY REVIEWS, 2020, 153 : 18 - 27
  • [20] Secondary Prevention Strategies for Nonmelanoma Skin Cancer
    Lopez, Adriana T.
    Carvajal, Richard D.
    Geskin, Larisa
    ONCOLOGY-NEW YORK, 2018, 32 (04): : 195 - 200
12345