Second-harmonic radiating imaging probes and harmonic holography

被引:2
作者
Pu, Ye [1 ]
Psaltis, Demetri [1 ]
机构
[1] Ecole Polytech Fed Lausanne, Sch Engn, Lab Opt, CH-1015 Lausanne, Switzerland
来源
ULTRAFAST NONLINEAR IMAGING AND SPECTROSCOPY IV | 2016年 / 9956卷
关键词
nonlinear optics; second harmonic generation; nanocrystals; holography; multiphoton imaging; two-photon microscopy; three-dimensional; NONLINEAR-OPTICAL PROPERTIES; IN-VIVO; PHASE-CONJUGATION; GENERATION; MICROSCOPY; NANOCRYSTALS; SCATTERING; RAMAN; EMISSION; TISSUE;
D O I
10.1117/12.2238511
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Compared with other imaging probes such as fluorescent dyes and quantum dots, second-harmonic radiating imaging probes (SHRIMPs) provide a unique ultrafast, coherent optical contrast that is free of photobleaching and emission intermittency. Using the second-harmonic signal emitted from SHRIMPs, harmonic holography achieves three-dimensional holographic imaging with a color contrast similar to fluorescence microscopy where the uninterested background scattering is efficiently suppressed by an optical filter. The coherent contrast provided by SHRIMPs also enables imaging through turbid media via digital phase conjugation. Here we review the developments and applications of SHRIMPs and harmonic holography.
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页数:13
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