Epilepsy surgery in children: Evaluation of seizure outcome and predictive elements

被引：28

作者：

Teutonico, Federica ^{[1
,2
]}

Mai, Roberto ^{[3
]}

Veggiotti, Pierangelo ^{[2
]}

Francione, Stefano ^{[3
]}

Tassi, Laura ^{[3
]}

Borrelli, Paola ^{[4
]}

Balottin, Umberto ^{[2
]}

LoRusso, Giorgio ^{[3
]}

机构：

[1] G Salvini Hosp, Child & Adolescence Neuropsychiat Unit, Rho, Italy

[2] Neurol Inst, Child & Adolescence Neuropsychiat Unit, Pavia, Italy

[3] Osped Niguarda Ca Granda, Epilepsy & Parkinson Surg Ctr C Munari, Milan, Italy

[4] Univ Pavia, Unit Biostat & Clin Epidemiol, Dept Publ Hlth Expt & Forens Med, I-27100 Pavia, Italy

来源：

EPILEPSIA | 2013年 / 54卷

关键词：

Children; Epilepsy surgery; Outcome; Presurgical evaluation; FOCAL CORTICAL DYSPLASIA; INTRACTABLE EPILEPSY; MALFORMATIONS;

D O I：

10.1111/epi.12312

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

PurposeTo analyze the clinical outcome of epilepsy surgery in children, and to identify the factors related with a favorable seizure control among several presurgical, surgical and postsurgical variables. MethodsOne-hundred twenty children, younger than 16years (69 male and 51 female), operated on for medically refractory focal epilepsy at the C.Munari Epilepsy Surgery Center of the Niguarda Hospital in Milan from 1998 to 2009, were identified. Seizure outcome was assessed according to the Engel's classification. Statistical analysis was performed to identify predictive elements of seizure outcome among several presurgical, surgical, and postsurgical variables. Key findingsThere were 84 (70%) seizure-free patients (Engel's classes Ia and Ic), 93 (77.5%) in class I, 8 (6.7%) in class II, 9 in class III (7.5%), and 10 (8.3%) in class IV. SignificanceOur study confirms that epilepsy surgery is an established and effective treatment for partial epilepsy in children and suggest criteria to help identify early potential surgical candidates.

引用

页码：70 / 76

页数：7

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