Effects of deltamethrin on lipid peroxidation in mice

被引:0
作者
Yarsan, E [1 ]
Bilgili, A
Kanbur, M
Celik, S
机构
[1] Ankara Univ, Fac Med Vet, Dept Pharmacol & Toxicol, TR-06011 Ankara, Turkey
[2] Mustafa Kemal Univ, Fac Vet Med, Dept Biochem, TR-06110 Hatay, Turkey
关键词
D O I
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中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Effects of deltamethrin on lipid peroxidation were investigated for subacute. subchronic and chronic periods. Deltamethrin was given to Swiss Albino mice at 1.5, 2.5, or 7.5 mg/kg. Lipid peroxidation was evaluated by determining malondialdehyde (MDA) levels in plasma, and determining glutathione peroxidase (GSH-Px), superoxide dismutase (Cu-Zn SOD) and catalase activities in erythrocytes on days 15, 45, and 60. MDA levels increased in deltamethrin dosed groups, especially for the subchronic and chronic periods. GSH-Px, Cu-Zn SOD and catalase activities in erythrocytes were decreased at high doses of deltamethrin, especially at the high dose (7.5 mg/kg) deltamethrin group.
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页码:73 / 75
页数:3
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