Agarose-stabilized gold nanoparticles for surface-enhanced Raman spectroscopic detection of DNA nucleosides

被引：44
|
作者：
Kattumuri, V [1 ]
Chandrasekhar, M
Guha, S
Raghuraman, K
Katti, KV
Ghosh, K
Patel, RJ
机构：
[1] Univ Missouri, Dept Phys & Astron, Columbia, MO 65211 USA
[2] Univ Missouri, Dept Radiol, Columbia, MO 65211 USA
[3] Missouri State Univ, Dept Phys, Springfield, MO 65804 USA
[4] Missouri State Univ, CASE, Springfield, MO 65804 USA
来源：
APPLIED PHYSICS LETTERS | 2006年 / 88卷 / 15期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1063/1.2192573
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
We present surface-enhanced Raman scattering (SERS) studies of DNA nucleosides using biologically benign agarose-stabilized gold nanoparticles (AAuNP). We compare the SERS activity of nucleosides with AAuNP to that of commercially obtained citrate-stabilized gold nanoparticles and find the SERS activity to be an order of magnitude higher with AAuNP. The higher SERS activity is explained in terms of the agarose matrix, which provides pathways for the gold nanoparticles to have distinct arrangements that result in stronger internal plasmon resonances.
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页数：3
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