Numerical design of a 3D microfluidic systems for bioparticle analysis: electrostatic and dielectrophoretic simulations

被引：0
|
作者：
Corman, Ramona [1 ,2 ]
Nedelcu, Oana [1 ]
Ravariu, Cristian [2 ]
机构：
[1] Natl Inst Res & Dev Microtechnol IMT Bucharest, Voluntari, Romania
[2] Univ Politehn Bucuresti, Elect Devices Circuits & Architectures Dept, Fac Elect Telecommun & Informat Technol, Bucharest, Romania
来源：
2016 39TH INTERNATIONAL SEMICONDUCTOR CONFERENCE (CAS) | 2016年
关键词：
microfluidics; cell manipulation; electric field; electroporation; SEPARATION; CELLS;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Development of in vitro techniques for medical and industrial applications has introduced over the past few years modern devices for detecting and manipulation of biological probes. A major interest is granted for unicellular analysis in order to produce new techniques for cell membrane permeabilization. Microfluidics became an indispensable tool used in cell research and analysis. In this paper, we present a new device for cell manipulation, electroporation and observation. Dielectrophoresis (DEP) is used to transport the cells by dielectroforetic forces (FDEP). The influence of electric field and flow behavior is studied. The simulation results show the influence of flow and dielectrophoretic force on cells migration inside the microfluidics channel.
引用
收藏
页码：187 / 190
页数：4
相关论文
共 50 条
  • [1] 3D droplet displacement in microfluidic systems by electrostatic actuation
    Roux, Jean-Maxime
    Fouillet, Yves
    Achard, Jean-Luc
    SENSORS AND ACTUATORS A-PHYSICAL, 2007, 134 (02) : 486 - 493
  • [2] Review: Microbial analysis in dielectrophoretic microfluidic systems
    Fernandez, Renny E.
    Rohani, Ali
    Farmehini, Vahid
    Swami, Nathan S.
    ANALYTICA CHIMICA ACTA, 2017, 966 : 11 - 33
  • [3] Dielectrophoretic microfluidic chip with 3D vertical side-wall electrodes
    Ji, Xiumin
    Pan, Jian
    Zhou, Jia
    2016 13TH IEEE INTERNATIONAL CONFERENCE ON SOLID-STATE AND INTEGRATED CIRCUIT TECHNOLOGY (ICSICT), 2016, : 269 - 271
  • [4] Biofluid Behaviour in 3D Microchannel Systems: Numerical Analysis and Design Development of 3D Microchannel Biochip Separators
    Xue, Xiangdong
    Marson, Silvia
    Patel, Mayur K.
    Attia, Usama M.
    Bailey, Chris
    O'Neill, William
    Topham, David
    Desmulliez, Marc P. Y.
    2010 PROCEEDINGS 60TH ELECTRONIC COMPONENTS AND TECHNOLOGY CONFERENCE (ECTC), 2010, : 1021 - 1030
  • [5] Dielectrophoretic motion of a red blood cell in a microfluidic environment: Insights from numerical simulations
    Ranjbaran, Azam
    PHYSICS OF FLUIDS, 2024, 36 (06)
  • [6] Development of a 3D Graphene Electrode Dielectrophoretic Device
    Xie, Hongyu
    Tewari, Radheshyam
    Fukushima, Hiroyuki
    Narendra, Jeffri
    Heldt, Caryn
    King, Julia
    Minerick, Adrienne R.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2014, (88):
  • [7] Colloidal assembly and 3D shaping by dielectrophoretic confinement
    Demirors, Ahmet Faik
    Crassous, Jerome J.
    SOFT MATTER, 2017, 13 (17) : 3182 - 3189
  • [8] Continuous dielectrophoretic particle separation using a microfluidic device with 3D electrodes and vaulted obstacles
    Jia, Yankai
    Ren, Yukun
    Jiang, Hongyuan
    ELECTROPHORESIS, 2015, 36 (15) : 1744 - 1753
  • [9] Electric field distribution analysis for the design of an electrode system in a 3D neuromuscular junction microfluidic device
    Forconi, Flavia
    Apa, Ludovica
    D'Alvia, Livio
    Cosentino, Marianna
    Rizzuto, Emanuele
    Del Prete, Zaccaria
    2021 IEEE INTERNATIONAL SYMPOSIUM ON MEDICAL MEASUREMENTS AND APPLICATIONS (IEEE MEMEA 2021), 2021,
  • [10] FABRICATION OF 3D DIAMOND MEMBRANES FOR MICROFLUIDIC SYSTEMS
    Varga, Marian
    Babchenko, Oleg
    Bauerova, Pavla
    Hruska, Karel
    Jurka, Vlastimil
    Kromka, Alexander
    Rezek, Bohuslav
    NANOCON 2014, 6TH INTERNATIONAL CONFERENCE, 2015, : 556 - 562
12345