CD226 Throttles up CD8+ T Cell Antitumor Activity

被引：3

作者：

Philip, Mary ^{[1
,2
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Div Hematol & Oncol, Dept Med, Nashville, TN 37232 USA

[2] Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA

来源：

IMMUNITY | 2020年 / 53卷 / 04期

关键词：

ACTIVATION; LYMPHOCYTES;

D O I：

10.1016/j.immuni.2020.09.013

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this issue of Immunity, Weulersse et al. and Braun et al. explain how CD226 expression loss on CD8(+) T cells impairs TCR-driven activation, and thereby anti-tumor effector responses, tantamount to taking the CD8(+) T cell's foot off the gas pedal.

引用

页码：704 / 706

页数：4

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