A miniaturized endocardial electromagnetic energy harvester for leadless cardiac pacemakers

被引:22
作者
Franzina, Nicolas [1 ,2 ]
Zurbuchen, Adrian [2 ]
Zumbrunnen, Andreas [1 ,3 ]
Niederhauser, Thomas [4 ]
Reichlin, Tobias [1 ]
Burger, Juergen [2 ]
Haeberlin, Andreas [1 ,2 ,3 ]
机构
[1] Univ Bern, Bern Univ Hosp, Dept Cardiol, Bern, Switzerland
[2] Univ Bern, Sitem Ctr Translat Med & Biomed Entrepreneurship, Bern, Switzerland
[3] Univ Bern, ARTORG Ctr Biomed Engn, Bern, Switzerland
[4] Bern Univ Appl Sci, Inst Human Ctr Engn, Biel, Switzerland
关键词
THERAPY; HEART;
D O I
10.1371/journal.pone.0239667
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Life expectancy of contemporary cardiac pacemakers is limited due to the use of an internal primary battery. Repeated device replacement interventions are necessary, which leads to an elevated risk for patients and an increase of health care costs. The aim of our study is to investigate the feasibility of powering an endocardial pacemaker by converting a minimal amount of the heart's kinetic energy into electric energy. The intrinsic cardiac muscle activity makes it an ideal candidate as continuous source of energy for endocardial pacemakers. For this reason, we developed a prototype able to generate enough power to supply a pacing circuit at different heart rates. The prototype consists of a mass imbalance that drives an electromagnetic generator while oscillating. We developed a mathematical model to estimate the amount of energy harvested from the right ventricle. Finally, the implemented prototype was successfully tested during in-vitro and in-vivo experiments.
引用
收藏
页数:19
相关论文
共 26 条
[1]  
[Anonymous], Guide for the care and use of laboratory animals, DOI 10.17226/12910
[2]  
[Anonymous], 2017, EUR J TRANSL MYOL, V27, p7X
[3]   A sub-cc nonlinear piezoelectric energy harvester for powering leadless pacemakers [J].
Ansari, M. H. ;
Karami, M. Amin .
JOURNAL OF INTELLIGENT MATERIAL SYSTEMS AND STRUCTURES, 2018, 29 (03) :438-445
[4]   Experimental investigation of fan-folded piezoelectric energy harvesters for powering pacemakers [J].
Ansari, M. H. ;
Karami, M. Amin .
SMART MATERIALS AND STRUCTURES, 2017, 26 (06)
[5]   Micro Blood Pressure Energy Harvester for Intracardiac Pacemaker [J].
Deterre, Martin ;
Lefeuvre, Elie ;
Zhu, Yanan ;
Woytasik, Marion ;
Boutaud, Bertrand ;
Dal Molin, Renzo .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2014, 23 (03) :651-660
[6]  
Ebrille Elisa, 2016, Indian Pacing Electrophysiol J, V16, P19, DOI 10.1016/j.ipej.2016.02.013
[7]   A Review on Mechanisms for Piezoelectric-Based Energy Harvesters [J].
Elahi, Hassan ;
Eugeni, Marco ;
Gaudenzi, Paolo .
ENERGIES, 2018, 11 (07)
[8]   Assessment of left ventricular dyssynchrony in pacing-induced left bundle branch block compared with intrinsic left bundle branch block [J].
Ghani, Abdul ;
Delnoy, Peter Paul H. M. ;
Ottervanger, Jan Paul ;
Misier, Anand R. Ramdat ;
Smit, Jaap Jan J. ;
Elvan, Arif .
EUROPACE, 2011, 13 (10) :1504-1507
[9]   Leadless pacemaker implantation quality: importance of the operator's experience [J].
Haeberlin, Andreas ;
Kozhuharov, Nikola ;
Knecht, Sven ;
Tanner, Hildegard ;
Schaer, Beat ;
Noti, Fabian ;
Osswald, Stefan ;
Servatius, Helge ;
Baldinger, Samuel ;
Seiler, Jens ;
Lam, Anna ;
Mosher, Luke ;
Sticherling, Christian ;
Roten, Laurent ;
Kuhne, Michael ;
Reichlin, Tobias .
EUROPACE, 2020, 22 (06) :939-946
[10]  
Herbawi AS, 2013, ULTRALOW POWER ACTIV, DOI [10.1109/ICSENS.2013.6688610, DOI 10.1109/ICSENS.2013.6688610]