'What's in the NIDDK CDR?'-public query tools for the NIDDK central data repository

被引：4

作者：

Pan, Huaqin ^{[1
]}

Ardini, Mary-Anne ^{[1
]}

Bakalov, Vesselina ^{[1
]}

DeLatte, Michael ^{[1
]}

Eggers, Paul ^{[2
]}

Ganapathi, Laxminarayana ^{[1
]}

Hollingsworth, Craig R. ^{[1
]}

Levy, Joshua ^{[1
]}

Li, Sheping ^{[1
]}

Pratt, Joseph ^{[1
]}

Pugh, Norma ^{[1
]}

Qin, Ying ^{[1
]}

Rasooly, Rebekah ^{[2
]}

Ray, Helen ^{[1
]}

Richardson, Jean E. ^{[1
]}

Riley, Amanda Flynn ^{[1
]}

Rogers, Susan M. ^{[1
]}

Tan, Sylvia ^{[1
]}

Turner, Charles F. ^{[1
,3
,4
]}

White, Stacie ^{[1
]}

Cooley, Philip C. ^{[1
]}

机构：

[1] RTI Int Social Stat & Environm Sci, Res Triangle Pk, NC 27709 USA

[2] NIDDK, Div Kidney Urol & Hematol Dis, Bethesda, MD 20892 USA

[3] CUNY Queens Coll, Flushing, NY 11367 USA

[4] CUNY Grad Ctr, Flushing, NY 11367 USA

来源：

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION | 2013年

关键词：

D O I：

10.1093/database/bas058

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The National Institute of Diabetes and Digestive Disease (NIDDK) Central Data Repository (CDR) is a web-enabled resource available to researchers and the general public. The CDR warehouses clinical data and study documentation from NIDDK funded research, including such landmark studies as The Diabetes Control and Complications Trial (DCCT, 1983-93) and the Epidemiology of Diabetes Interventions and Complications (EDIC, 1994-present) follow-up study which has been ongoing for more than 20 years. The CDR also houses data from over 7 million biospecimens representing 2 million subjects. To help users explore the vast amount of data stored in the NIDDK CDR, we developed a suite of search mechanisms called the public query tools (PQTs). Five individual tools are available to search data from multiple perspectives: study search, basic search, ontology search, variable summary and sample by condition. PQT enables users to search for information across studies. Users can search for data such as number of subjects, types of biospecimens and disease outcome variables without prior knowledge of the individual studies. This suite of tools will increase the use and maximize the value of the NIDDK data and biospecimen repositories as important resources for the research community. Database URL:https://www.niddkrepository.org/niddk/home.do

引用

页数：11

共 5 条

[1] NIDDK data repository: A central collection of clinical trial data [J].

Cuticchia A.J. ;

Cooley P.C. ;

Hall R.D. ;

Qin Y. .

BMC Medical Informatics and Decision Making, 6 (1)

[2] The NCBI dbGaP database of genotypes and phenotypes [J].

Mailman, Matthew D. ;

Feolo, Michael ;

Jin, Yumi ;

Kimura, Masato ;

Tryka, Kimberly ;

Bagoutdinov, Rinat ;

Hao, Luning ;

Kiang, Anne ;

Paschall, Justin ;

Phan, Lon ;

Popova, Natalia ;

Pretel, Stephanie ;

Ziyabari, Lora ;

Lee, Moira ;

Shao, Yu ;

Wang, Zhen Y. ;

Sirotkin, Karl ;

Ward, Minghong ;

Kholodov, Michael ;

Zbicz, Kerry ;

Beck, Jeffrey ;

Kimelman, Michael ;

Shevelev, Sergey ;

Preuss, Don ;

Yaschenko, Eugene ;

Graeff, Alan ;

Ostell, James ;

Sherry, Stephen T. .

NATURE GENETICS, 2007, 39 (10) :1181-1186

[3]

Massett Holly A., 2011, Journal of the National Cancer Institute Monographs, P8, DOI 10.1093/jncimonographs/lgr007

[4]

Shea K., 2010, BIOLINCC ISBER NEWS, V10, P5

[5] The NIDDK Central Repository at 8 years-Ambition, Revision, Use and Impact [J].

Turner, Charles F. ;

Pan, Huaqin ;

Silk, Gregg W. ;

Ardini, Mary-Anne ;

Bakalov, Vesselina ;

Bryant, Stephanie ;

Cantor, Susanna ;

Chang, Kung-yen ;

DeLatte, Michael ;

Eggers, Paul ;

Ganapathi, Laxminarayana ;

Lakshmikanthan, Sujatha ;

Levy, Joshua ;

Li, Sheping ;

Pratt, Joseph ;

Pugh, Norma ;

Qin, Ying ;

Rasooly, Rebekah ;

Ray, Helen ;

Richardson, Jean E. ;

Riley, Amanda Flynn ;

Rogers, Susan M. ;

Scheper, Charlotte ;

Tan, Sylvia ;

White, Stacie ;

Cooley, Philip C. .

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2011,

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