Diagnosis of Schistosoma haematobium Infection with a Mobile Phone-Mounted Foldscope and a Reversed-Lens CellScope in Ghana

被引：65

作者：

Ephraim, Richard K. D. ^{[1
]}

Duah, Evans ^{[1
]}

Cybulski, James S. ^{[2
,3
]}

Prakash, Manu ^{[2
,3
]}

D'Ambrosio, Michael V. ^{[4
]}

Fletcher, Daniel A. ^{[4
]}

Keiser, Jennifer ^{[5
,6
]}

Andrews, Jason R. ^{[7
]}

Bogoch, Isaac I. ^{[8
,9
]}

机构：

[1] Univ Cape Coast, Div Med Lab Technol, Cape Coast, Ghana

[2] Stanford Univ, Dept Mech Engn, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA

[4] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

[5] Swiss Trop & Publ Hlth Inst, Dept Med Parasitol & Infect Biol, Basel, Switzerland

[6] Univ Basel, Basel, Switzerland

[7] Stanford Univ, Sch Med, Div Infect Dis & Geog Med, Stanford, CA 94305 USA

[8] Toronto Gen Hosp, Div Internal Med, Toronto, ON M5G 2C4, Canada

[9] Toronto Gen Hosp, Div Infect Dis, Toronto, ON M5G 2C4, Canada

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2015年 / 92卷 / 06期

基金：

美国国家科学基金会;

关键词：

TRANSMITTED HELMINTH INFECTIONS; FILTRATION; MICROSCOPY; URINE; EGGS;

D O I：

10.4269/ajtmh.14-0741

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We evaluated two novel, portable microscopes and locally acquired, single-ply, paper towels as filter paper for the diagnosis of Schistosoma haematobium infection. The mobile phone-mounted Foldscope and reversed-lens CellScope had sensitivities of 55.9% and 67.6%, and specificities of 93.3% and 100.0%, respectively, compared with conventional light microscopy for diagnosing S. haernatobium infection. With conventional light microscopy, urine filtration using single-ply paper towels as filter paper showed a sensitivity of 67.6% and specificity of 80.0% compared with centrifugation for the diagnosis of S. haematobium infection. With future improvements to diagnostic sensitivity, newer generation handheld and mobile phone microscopes may be valuable tools for global health applications.

引用

页码：1253 / 1256

页数：4

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