Electrochemical initiation of electron-catalyzed phenanthridine synthesis by trifluoromethylation of isonitriles

被引：53

作者：

Luebbesmeyer, M. ^{[1
]}

Leifert, D. ^{[1
]}

Schaefer, H. ^{[1
]}

Studer, A. ^{[1
]}

机构：

[1] Westfal Wilhelms Univ Munster, Corrensstr 40, D-48149 Munster, Germany

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 18期

基金：

欧洲研究理事会;

关键词：

AROMATIC-SUBSTITUTION BHAS; METAL-FREE CONDITIONS; RADICAL TRIFLUOROMETHYLATION; PERFLUOROALKYL RADICALS; NITROGEN-HETEROCYCLES; VINYL AZIDES; DERIVATIVES; ISOCYANIDES; 6-TRIFLUOROMETHYL-PHENANTHRIDINES; ISOMERIZATION;

D O I：

10.1039/c7cc09302k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The electron-catalyzed formation of phenanthridines starting from isonitriles initiated by an electrochemical reduction of the Togni reagent is presented. The required number of faradays per mole of starting material and the respective yields clearly show the catalytic character of the electron in this reaction. The mechanism is supported by cyclic voltammetry experiments.

引用

页码：2240 / 2243

页数：4

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