CHITOSAN-POLYVINILPYRROLIDONE/ELLAGIC ACID BASED MEMBRANES WITH CONTROLLED ANTIOXIDANT PROPERTIES

被引：0

作者：

Neagu, Elena ^{[1
]}

Paun, Gabriela ^{[1
]}

Alecu, Andreia ^{[1
]}

Radu, Gabriel Lucian ^{[2
]}

机构：

[1] Natl Inst Res Dev Biol Sci, Ctr Bioanal, Bucharest 060031 6, Romania

[2] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Bucharest 060042, Romania

来源：

REVUE ROUMAINE DE CHIMIE | 2013年 / 58卷 / 9-10期

关键词：

membrane; chitosan; ellagic acid; FTIR; entrapping; antioxidant; ELLAGIC ACID; DRUG-DELIVERY; HUMAN COLON; ENCAPSULATION; RELEASE; BEADS; NANOPARTICLES; APOPTOSIS; BEHAVIOR; EXTRACT;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

They were characterized by Fourier transform infrared spectroscopy (FTIR). The efficiency of EA entrapment revealed values >= 50%. The released ellagic acid quantities were spectrophotometrically determined at various time intervals: 1, 2, 3, 7 days, and various pH: 3.0, 7.5, 8.0, 9.0. The best cumulative release of ellagic acid from membranes was obtained at lowest pH, pH=3. The antioxidant capacity of EA released from membranes was evaluated by inhibition percent of 2,2-diphenyl-1-picrylhydrazyl (DPPH). The best result was found also at pH=3.0, 20% DPPH inhibition (at 48h). The properties of such membranes recommend them as biomaterial with controlled antioxidant biological activity.

引用

页码：791 / +

页数：8

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