Pestaloporonins: Caryophyllene-Derived Sesquiterpenoids from a Fungicolous Isolate of Pestalotiopsis sp.

被引：19

作者：

Hwang, In Hyun ^{[1
]}

Swenson, Dale C. ^{[1
]}

Gloer, James B. ^{[1
]}

Wicklow, Donald T. ^{[2
]}

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Bacterial Foodborne Pathogens & Mycol Res Unit, Peoria, IL 61604 USA

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 17期

基金：

美国国家科学基金会;

关键词：

FUNGUS PORONIA-PUNCTATA; TAXUS-BREVIFOLIA; METABOLITES; PUNCTAPORONINS; REARRANGEMENT; ASPERGILLUS; MARINE;

D O I：

10.1021/acs.orglett.5b02080

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new sesquiterpenoids (pestaloporonins A C ; 1-3) related to the caryophyllene-derived punctaporonins were isolated from cultures of a fungicolous isolate of Pestalotiopsis sp. The structures of 1-3 were determined by analysis of NMR and HRMS data, and the structure of 1, including its absolute configuration, was confirmed by X-ray crystallographic analysis. Compounds 1 and 2 contain new bicyclic and tricyclic ring systems, respectively.

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页码：4284 / 4287

页数：4

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