NBu4SH provides a convenient source of HS- soluble in organic solution for H2S and anion-binding research

被引：31

作者：

Hartle, Matthew D. ^{[1
]}

Meininger, Daniel J. ^{[2
]}

Zakharov, Lev N. ^{[1
]}

Tonzetich, Zachary J. ^{[2
]}

Pluth, Michael D. ^{[1
]}

机构：

[1] Inst Mol Biol, Inst Mat Sci, Dept Chem & Biochem, Eugene, OR 97403 USA

[2] Univ Texas San Antonio, Dept Chem, San Antonio, TX 78249 USA

来源：

DALTON TRANSACTIONS | 2015年 / 44卷 / 46期

基金：

美国国家科学基金会;

关键词：

HYDROGEN-SULFIDE; S-NITROSOTHIOLS; HYDROSULFIDE; CHEMISTRY; NO; BIOACTIVITY; REACTIVITY; COMPLEXES; OXIDATION; RECEPTOR;

D O I：

10.1039/c5dt03355a

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Hydrogen sulfide (H2S) has gained significant interest within the scientific community due to its expanding roles in different (patho) physiological processes. Despite this importance, the chemical mechanisms by which H2S exerts its action remain under-scrutinized. Biomimetic investigations in organic solution offer the potential to clarify these mechanisms and to delineate the differential reactivity between H2S and HS-. However, such studies are hampered by the lack of readily-available sources of HS- that are soluble in organic solution. Here we present a simple method for preparing analytically pure tetrabutylammonium hydrosulfide (NBu4SH), which we anticipate will be of significant utility to researchers in the H2S and anion-binding communities.

引用

页码：19782 / 19785

页数：4