Selective Ruthenium-Catalyzed Transfer Hydrogenations of Nitriles to Amines with 2-Butanol

被引：54
作者：
Werkmeister, Svenja [1 ]
Bornschein, Christoph [1 ]
Junge, Kathrin [1 ]
Beller, Matthias [1 ]
机构：
[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 14期
关键词：
amines; nitriles; phosphane ligands; ruthenium; transfer hydrogenation; ASYMMETRIC TRANSFER HYDROGENATION; BIOMIMETIC TRANSFER HYDROGENATION; IRON-PORPHYRIN CATALYSTS; HYDRIDE COMPLEXES; REDUCTION; LIGANDS; KETONES; ALKYNES; HYDROAMINATION; BENZONITRILE;
D O I：
10.1002/chem.201204633
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Transfer your hydrogen: Fast and general transfer hydrogenation of nitriles to form primary amines is possible with a homogeneous Ru/1,4- bis(diphenylphosphino)butane (DPPB) catalyst (see scheme). The use of 2-butanol as the hydrogen-transfer reagent is essential for the selective reduction of aromatic, heteroaromatic, and aliphatic nitriles with this system. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：4437 / 4440
页数：4
相关论文
共 49 条
  • [1] Ruthenium N-heterocyclic carbene catalysts for selective reduction of nitriles to primary amines
    Addis, Daniele
    Enthaler, Stephan
    Junge, Kathrin
    Wendt, Bianca
    Beller, Matthias
    [J]. TETRAHEDRON LETTERS, 2009, 50 (26) : 3654 - 3656
  • [2] [Anonymous], 2012, ANGEW CHEM-GER EDIT, DOI DOI 10.1002/ANGE.201202584
  • [3] [Anonymous], 2010, ANGEW CHEM-GER EDIT
  • [4] Preparation, characterization, and performance of the supported hydrogen-bonded ruthenium catalyst [(sulphos)Ru(NCMe)3](OSO2CF3)/SiO2.: Comparisons with analogous homogeneous and aqueous-biphase catalytic systems in the hydrogenation of benzylideneacetone and benzonitrile
    Bianchini, C
    Dal Santo, V
    Meli, A
    Oberhauser, W
    Psaro, R
    Vizza, F
    [J]. ORGANOMETALLICS, 2000, 19 (13) : 2433 - 2444
  • [5] Blaser H.-U., 2007, HDB HOMOGENEOUS HYDR, V3, P1193
  • [6] Selective hydrogenation for fine chemicals: Recent trends and new developments
    Blaser, HU
    Malan, C
    Pugin, B
    Spindler, F
    Steiner, H
    Studer, M
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2003, 345 (1-2) : 103 - 151
  • [7] BROWN GR, 1982, SYNTHESIS-STUTTGART, P1036
  • [8] Hydrogen transfer reduction of nitriles in DBU based ionic liquids
    Chen, Xinzhi
    Zhou, Shaodong
    Qian, Chao
    [J]. ARKIVOC, 2012, : 128 - 136
  • [9] Chin C.S., 1992, CATAL LETT, V14, P135, DOI DOI 10.1007/BF00764228
  • [10] Mechanisms of the H2-hydrogenation and transfer hydrogenation of polar bonds catalyzed by ruthenium hydride complexes
    Clapham, SE
    Hadzovic, A
    Morris, RH
    [J]. COORDINATION CHEMISTRY REVIEWS, 2004, 248 (21-24) : 2201 - 2237
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