The aim of this study was to investigate vestibular evoked myogenic potentials (VEMPs) and their clinical significance in Behcet's disease. Twenty-six patients with Behcet's disease and 25 healthy volunteers were evaluated for pure tone audiometry, caloric response, and VEMPs. Sensorineural hearing loss was found in 53.8% of patients with Behcet's disease, which was significantly higher than controls. Four patients had canal paresis, but no controls; this difference was not significant. Although VEMP recordings were elicited in all study subjects, mean p13 and n23 latencies were prolonged in Behcet's patients compared with controls. Seven patients had delayed VEMP responses. There were no correlations regarding p13 values and age, duration or activity of disease, vertigo, or sensorineural hearing loss. The results of this preliminary study suggest an association between delayed VEMP responses and Behcet's disease. Further research with large samples is needed to confirm that VEMP testing is useful to diagnose and follow vestibular dysfunction in Behcet's disease.
机构:
Royal Prince Alfred Hosp, Neurol Dept, Sydney, NSW, Australia
Univ Sydney, Cent Clin Sch, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Neurol Dept, Sydney, NSW, Australia
Rosengren, Sally M.
Welgampola, Miriam S.
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Univ Sydney, Cent Clin Sch, Sydney, NSW, Australia
Royal Prince Alfred Hosp, Inst Clin Neurosci, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Neurol Dept, Sydney, NSW, Australia
Welgampola, Miriam S.
Taylor, Rachael L.
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Whangarei Hosp, Audiol Dept, Whangarei, New Zealand
New Zealand Dizziness & Balance Ctr, Auckland, New ZealandRoyal Prince Alfred Hosp, Neurol Dept, Sydney, NSW, Australia
机构:
Univ Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, ItalyUniv Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, Italy
Magliulo, Giuseppe
Parrotto, Donato
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Univ Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, ItalyUniv Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, Italy
Parrotto, Donato
Gagliardi, Mario
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Univ Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, ItalyUniv Roma La Sapienza, Dept Otorhinolaryngol Audiol & Phoniatr G Ferreri, Rome, Italy