Manganese complex-catalysed α-alkylation of ketones with secondary alcohols enables the synthesis of β-branched carbonyl compounds

被引:56
作者
Waiba, Satyadeep [1 ]
Jana, Sayan K. [1 ]
Jati, Ayan [1 ]
Jana, Akash [1 ]
Maji, Biplab [1 ]
机构
[1] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, India
关键词
BORROWING HYDROGEN; ACTIVATION; ESTERS; AMIDES;
D O I
10.1039/d0cc01460e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein, beta-branched carbonyl compounds were synthesisedviathe alpha-alkylation of ketones with secondary alcohols under "borrowing hydrogen" catalysis. A wide range of secondary alcohols, including various cyclic, acyclic, symmetrical, and unsymmetrical alcohols, have been successfully applied under the developed reaction conditions. A manganese(i) complex bearing a phosphine-free multifunctional ligand catalysed the reaction and produced water as the sole byproduct.
引用
收藏
页码:8376 / 8379
页数:4
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