Manganese complex-catalysed α-alkylation of ketones with secondary alcohols enables the synthesis of β-branched carbonyl compounds

被引：56

作者：

Waiba, Satyadeep ^{[1
]}

Jana, Sayan K. ^{[1
]}

Jati, Ayan ^{[1
]}

Jana, Akash ^{[1
]}

Maji, Biplab ^{[1
]}

机构：

[1] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, India

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 60期

关键词：

BORROWING HYDROGEN; ACTIVATION; ESTERS; AMIDES;

D O I：

10.1039/d0cc01460e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, beta-branched carbonyl compounds were synthesisedviathe alpha-alkylation of ketones with secondary alcohols under "borrowing hydrogen" catalysis. A wide range of secondary alcohols, including various cyclic, acyclic, symmetrical, and unsymmetrical alcohols, have been successfully applied under the developed reaction conditions. A manganese(i) complex bearing a phosphine-free multifunctional ligand catalysed the reaction and produced water as the sole byproduct.

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收藏

页码：8376 / 8379

页数：4

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