Facile fabrication of gold particles decorated silk-on-silk nanocapsules

被引：5

作者：

Du, Bo ^{[1
,2
]}

Wang, Hongwei ^{[1
,2
,3
]}

Tang, Hongbo ^{[4
]}

Guan, Man ^{[1
,2
]}

Wang, Jingjie ^{[1
,2
]}

Zhang, Zhe ^{[1
,2
]}

Zhou, Zhimin ^{[1
,2
]}

Zhang, Qiqing ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, Inst Biomed Engn, Tianjin 300192, Peoples R China

[2] Peking Union Med Coll, Tianjin Key Lab Biomed Mat, Tianjin 300192, Peoples R China

[3] Chengde Med Univ, Inst Chinese Mat Med, Hebei Key Lab Res & Dev Tradit Chinese Med, Chengde 067000, Hebei, Peoples R China

[4] Capital Med Univ, Beijing Obstet & Gynecol Hosp, Dept Pharm, Beijing 100026, Peoples R China

来源：

MATERIALS LETTERS | 2017年 / 187卷

关键词：

Biomaterials; Silk nanocapsules; Gold; Nanoparticles; Layer-by-layer; Hybridization; MICROCAPSULES; NANORODS; LIPOSOMES; DESOLVATION; RELEASE;

D O I：

10.1016/j.matlet.2016.08.155

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Both protein capsules and gold nanoparticles have attracted considerable attention in drug delivery systems. In this study, silk fibroin nanocapsules were fabricated by silk-on-silk layer-by-layer (LbL) assembly onto poly[lactic-co-(glycolic acid)] (PLGA) sacrificial templates followed by core removal. Subsequently, hybrid nanocapsules were fabricated by physical adsorption of DNA modified gold nanospheres and nanorods. These hybrid LbL-nanocapsules have potential applications for targeted drug delivery or combination therapy.

引用

页码：106 / 110

页数：5

共 22 条

[1] The enhanced longevity and liver targetability of Paclitaxel by hybrid liposomes encapsulating Paclitaxel-conjugated gold nanoparticles [J].

Bao, Quan-Ying ;

Zhang, Ning ;

Geng, Dong-Dong ;

Xue, Jing-Wei ;

Merritt, Mackenzie ;

Zhang, Can ;

Ding, Ya .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2014, 477 (1-2) :408-415

[2] Aptamer-based colorimetric detection of proteins using a branched DNA cascade amplification strategy and unmodified gold nanoparticles [J].

Chang, Chia-Chen ;

Chen, Chen-Yu ;

Chuang, Tsung-Liang ;

Wu, Tzu-Heng ;

Wei, Shu-Chen ;

Liao, Hongen ;

Lin, Chii-Wann .

BIOSENSORS & BIOELECTRONICS, 2016, 78 :200-205

[3] Polymer vesicles [J].

Discher, DE ;

Eisenberg, A .

SCIENCE, 2002, 297 (5583) :967-973

[4] Synthesis of silk-based microcapsules by desolvation and hybridization [J].

Du, Bo ;

Wang, Jingjie ;

Zhou, Zhimin ;

Tang, Hongbo ;

Li, Xuemin ;

Liu, Yingjie ;

Zhang, Qiqing .

CHEMICAL COMMUNICATIONS, 2014, 50 (34) :4423-4426

[5] Polymer hollow particles with controllable holes in their surfaces [J].

Im, SH ;

Jeong, UY ;

Xia, YN .

NATURE MATERIALS, 2005, 4 (09) :671-675

[6] Layer-by-layer engineered nanocapsules of curcumin with improved cell activity [J].

Kittitheeranun, Paveenuch ;

Sajomsang, Warayuth ;

Phanpee, Sarunya ;

Treetong, Alongkot ;

Wutikhun, Tuksadon ;

Suktham, Kunat ;

Puttipipatkhachorn, Satit ;

Ruktanonchai, Uracha Rungsardthong .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2015, 492 (1-2) :92-102

[7] Direct growth of optically stable gold nanorods onto polyelectrolyte multilayered capsules [J].

Koo, Hye Young ;

Choi, Won San ;

Kim, Dong-Yu .

SMALL, 2008, 4 (06) :742-745

[8] High-Yield Fabrication of PLGA Non-Spherical Microarchitectures by Emulsion-Solvent Evaporation Method [J].

Li, Ruifeng ;

Li, Xuemin ;

Liu, Lingrong ;

Zhou, Zhimin ;

Tang, Hongbo ;

Zhang, Qiqing .

MACROMOLECULAR RAPID COMMUNICATIONS, 2010, 31 (22) :1981-1986

[9]

Rivera Gil P, 2008, NANO TODAY, V3, P12

[10] Silk-on-Silk Layer-by-Layer Microcapsules [J].

Shchepelina, Olga ;

Drachuk, Irina ;

Gupta, Maneesh K. ;

Lin, Jeffrey ;

Tsukruk, Vladimir V. .

ADVANCED MATERIALS, 2011, 23 (40) :4655-+

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