Bone like apatite formation on modified Ti surfaces with COOH, NH2, and OH functional groups by plasma polymerization

被引：9
作者：
Ko, Yeong-Mu [1 ]
Lee, Kang [1 ]
Kim, Byung-Hoon [1 ]
机构：
[1] Chosun Univ, MRC Ctr, Sch Dent, Dept Dent Mat, Kwangju, South Korea
来源：
THIN SOLID FILMS | 2012年 / 521卷
关键词：
Bone like apatite; Titanium; Functional group; Plasma polymerization; SIMULATED BODY-FLUID; TITANIUM; PROTEINS; GEL;
D O I：
10.1016/j.tsf.2012.02.036
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HA) is materials mainly known for its special ability to contact bone tissue. In this study, bone like apatite formation was investigated at the titanium (Ti) surface with functional groups, -COOH, -NH2, and -OH respectively. Ti surface was modified by depositing a thin polymeric film containing COOH, NH2, and OH groups through plasma polymerization of acrylic acid, ally amine and allyl alcohol. Plasma polymerization carried out at a discharge power of 50 W for 5 min. Modified Ti samples were evaluated by immersed in simulated body fluid at 36.5 degrees C for 4 days and 7 days. COOH/Ti was favorable for bone-like apatite formation when compared with untreated Ti, NH2/Ti and OH/Ti. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：128 / 131
页数：4
相关论文
共 16 条
[1]   Acrylic acid grafting and collagen immobilization on poly(ethylene terephthalate) surfaces for adherence and growth of human bladder smooth muscle cells [J].
Bisson, I ;
Kosinski, M ;
Ruault, S ;
Gupta, B ;
Hilborn, J ;
Wurm, F ;
Frey, P .
BIOMATERIALS, 2002, 23 (15) :3149-3158
[2]   Biomedical surface science: Foundations to frontiers [J].
Castner, DG ;
Ratner, BD .
SURFACE SCIENCE, 2002, 500 (1-3) :28-60
[3]  
COOK SD, 1988, CLIN ORTHOP RELAT R, P225
[4]  
Favia P., 1998, Plasmas and Polymers, V3, P77, DOI DOI 10.1023/B:PAPO.0000005940.30092.58
[5]   Adhesion forces of the blood plasma proteins on self-assembled monolayer surfaces of alkanethiolates with different functional groups measured by an atomic force microscope [J].
Kidoaki, S ;
Matsuda, T .
LANGMUIR, 1999, 15 (22) :7639-7646
[6]  
Li P., 1992, T 4 WORLD BIOM C, P4
[7]   The optimal SAM surface functional group for producing a biomimetic HA coating on Ti [J].
Liu, D. P. ;
Majewski, P. ;
O'Neill, B. K. ;
Ngothai, Y. ;
Colby, C. B. .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2006, 77A (04) :763-772
[8]   Apatite-forming ability of niobium oxide gels in a simulated body fluid [J].
Miyazaki, T ;
Kim, HM ;
Kokubo, T ;
Ohtsuki, C ;
Nakamura, T .
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 2001, 109 (11) :929-933
[9]   Induction and acceleration of bonelike apatite formation on tantalum oxide gel in simulated body fluid [J].
Miyazaki, T ;
Kim, HM ;
Kokubo, T ;
Kato, H ;
Nakamura, T .
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2001, 21 (1-2) :83-88
[10]   A technique to immobilize bioactive proteins, including bone morphogenetic protein-4 (BMP-4), on titanium alloy [J].
Puleo, DA ;
Kissling, RA ;
Sheu, MS .
BIOMATERIALS, 2002, 23 (09) :2079-2087
12