Should clot composition affect choice of endovascular therapy?

被引:43
作者
Mehta, Brijesh P. [4 ]
Nogueira, Raul G. [1 ,2 ,3 ]
机构
[1] Emory Univ, Grady Hosp, Dept Neurol, Atlanta, GA 30322 USA
[2] Emory Univ, Grady Hosp, Dept Neurosurg, Atlanta, GA 30322 USA
[3] Emory Univ, Grady Hosp, Dept Radiol, Atlanta, GA 30322 USA
[4] Harvard Univ, Sch Med, Dept Neurol, Massachusetts Gen Hosp, Boston, MA 02115 USA
关键词
TISSUE-PLASMINOGEN-ACTIVATOR; ACUTE ISCHEMIC-STROKE; THROMBOLYSIS; THROMBI; TRIAL; ASSOCIATION; ARTERIES;
D O I
10.1212/WNL.0b013e3182695859
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Endovascular therapy has become a promising alternative for patients who are ineligible for IV thrombolysis or for whom it has failed. Greater knowledge about the composition of thromboembolic material underlying the vascular occlusion in stroke patients may provide the means for improving existing endovascular therapies and developing new treatment strategies. The objective of this article is to provide a review of clinical and experimental animal studies on the histology, imaging correlation, and ultrastructure of thromboemboli retrieved during acute ischemic stroke. Neurology (R) 2012; 79 (Suppl 1): S63-S67
引用
收藏
页码:S63 / S67
页数:5
相关论文
共 26 条
  • [11] CT and MRI Early Vessel Signs Reflect Clot Composition in Acute Stroke
    Liebeskind, David S.
    Sanossian, Nerses
    Yong, William H.
    Starkman, Sidney
    Tsang, Michael P.
    Moya, Antonio L.
    Zheng, David D.
    Abolian, Anna M.
    Kim, Doojin
    Ali, Latisha K.
    Shah, Samir H.
    Towfighi, Amytis
    Ovbiagele, Bruce
    Kidwell, Chelsea S.
    Tateshima, Satoshi
    Jahan, Reza
    Duckwiler, Gary R.
    Vinuela, Fernando
    Salamon, Noriko
    Villablanca, J. Pablo
    Vinters, Harry V.
    Marder, Victor J.
    Saver, Jeffrey L.
    [J]. STROKE, 2011, 42 (05) : 1237 - 1243
  • [12] Association of hyperdense middle cerebral artery sign with clinical outcome in patients treated with tissue plasminogen activator
    Manelfe, C
    Larrue, V
    von Kummer, R
    Bozzao, L
    Ringleb, P
    Bastianello, S
    Iweins, F
    Lesaffre, E
    [J]. STROKE, 1999, 30 (04) : 769 - 772
  • [13] Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke
    Marder, Victor J.
    Chute, Dennis J.
    Starkman, Sidney
    Abolian, Anna M.
    Kidwell, Chelsea
    Liebeskind, David
    Ovbiagele, Bruce
    Vinuela, Fernando
    Duckwiler, Gary
    Jahan, Reza
    Vespa, Paul M.
    Selco, Scott
    Rajajee, Venkatakrishna
    Kim, Dojin
    Sanossian, Nerses
    Saver, Jeffrey L.
    [J]. STROKE, 2006, 37 (08) : 2086 - 2093
  • [14] TISSUE-PLASMINOGEN ACTIVATOR FOR ACUTE ISCHEMIC STROKE
    MARLER, JR
    BROTT, T
    BRODERICK, J
    KOTHARI, R
    ODONOGHUE, M
    BARSAN, W
    TOMSICK, T
    SPILKER, J
    MILLER, R
    SAUERBECK, L
    JARRELL, J
    KELLY, J
    PERKINS, T
    MCDONALD, T
    RORICK, M
    HICKEY, C
    ARMITAGE, J
    PERRY, C
    THALINGER, K
    RHUDE, R
    SCHILL, J
    BECKER, PS
    HEATH, RS
    ADAMS, D
    REED, R
    KLEI, M
    HUGHES, S
    ANTHONY, J
    BAUDENDISTEL, D
    ZADICOFF, C
    RYMER, M
    BETTINGER, I
    LAUBINGER, P
    SCHMERLER, M
    MEIROSE, G
    LYDEN, P
    RAPP, K
    BABCOCK, T
    DAUM, P
    PERSONA, D
    BRODY, M
    JACKSON, C
    LEWIS, S
    LISS, J
    MAHDAVI, Z
    ROTHROCK, J
    TOM, T
    ZWEIFLER, R
    DUNFORD, J
    ZIVIN, J
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (24) : 1581 - 1587
  • [15] Extending Reperfusion therapy for acute ischemic stroke - Emerging pharmacological, mechanical, and imaging strategies
    Molina, CA
    Saver, JL
    [J]. STROKE, 2005, 36 (10) : 2311 - 2320
  • [16] Differences in clot preparation determine outcome of recombinant tissue plasminogen activator treatment in experimental thromboembolic stroke
    Niessen, F
    Hilger, T
    Hoehn, M
    Hossmann, KA
    [J]. STROKE, 2003, 34 (08) : 2019 - 2024
  • [17] Endovascular Approaches to Acute Stroke, Part 1: Drugs, Devices, and Data
    Nogueira, R. G.
    Schwamm, L. H.
    Hirsch, J. A.
    [J]. AMERICAN JOURNAL OF NEURORADIOLOGY, 2009, 30 (04) : 649 - 661
  • [18] Nogueira RG, 2008, INT STROK C
  • [19] Stroke as the first manifestation of calcific aortic stenosis
    Oliveira, J
    Massaro, AR
    Yamamoto, F
    Bustamante, L
    Scaff, M
    [J]. CEREBROVASCULAR DISEASES, 2000, 10 (05) : 413 - 416
  • [20] Safety and efficacy of mechanical embolectomy in acute ischemic stroke - Results of the MERCI trial
    Smith, WS
    Sung, G
    Starkman, S
    Saver, JL
    Kidwell, CS
    Gobin, YP
    Lutsep, HL
    Nesbit, GM
    Grobelny, T
    Rymer, MM
    Silverman, IE
    Higashida, RT
    Budzik, RF
    Marks, MP
    [J]. STROKE, 2005, 36 (07) : 1432 - 1438