Bioaerosols - more than just allergens: complex situations at workplaces Our breathing air does not only contain gases but also plenty of airborne particles of organic origin. These particles could affect the upper or lower respiratory tract in exposed persons and may cause irritative, toxic and/or allergic complaints. Up to now no quantification methods are available to assess the effects of bioaerosols on humans. In susceptible subjects the inhalation of allergens can be characterized by the induction of an IgE-mediated Type I sensitization. For non-allergenic components of organic dust no test systems exist that allows to assess the effect on exposed subjects. Besides indoor air exposure, especially the often quantitatively higher bioaerosol exposure at several workplaces plays an important role. For example, in agriculture, textile industry or at waste disposal workplaces complex bioaerosol exposure with variable composition occurs. Particularly with regard to the inflammatory and pyrogenic effects induced by bioaerosol inhalation only little information is available. This article summarizes options and their limits to characterize components of organic dust beyond their allergenic properties.
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Univ Penn, New Bolton Ctr, Sch Vet Med, Dept Pathobiol,Murphy Lab, Kennett Sq, PA 19348 USA
Univ Penn, New Bolton Ctr, Sch Vet Med, Dept Clin Studies, Kennett Sq, PA 19348 USAUniv Penn, New Bolton Ctr, Sch Vet Med, Dept Pathobiol,Murphy Lab, Kennett Sq, PA 19348 USA
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Res Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
German Ctr Lung Res DZL, Airway Res Ctr North, Borstel, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
Frey, Andreas
Lunding, Lars P.
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German Ctr Lung Res DZL, Airway Res Ctr North, Borstel, Germany
Res Ctr Borstel, Div Asthma Exacerbat & Regulat, Borstel, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
Lunding, Lars P.
Ehlers, Johanna C.
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German Ctr Lung Res DZL, Airway Res Ctr North, Borstel, Germany
Res Ctr Borstel, Div Expt Pneumol, Borstel, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
Ehlers, Johanna C.
Weckmann, Markus
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German Ctr Lung Res DZL, Airway Res Ctr North, Borstel, Germany
Univ Childrens Hosp, Dept Pediat Pulmonol & Allergol, Lubeck, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
Weckmann, Markus
Zissler, Ulrich M.
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Tech Univ Munich, Ctr Allergy & Environm ZAUM, Munich, Germany
Helmholtz Ctr Munich, German Res Ctr Environm Hlth, Munich, Germany
German Ctr Lung Res DZL, CPC M, Munich, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
Zissler, Ulrich M.
Wegmann, Michael
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German Ctr Lung Res DZL, Airway Res Ctr North, Borstel, Germany
Res Ctr Borstel, Div Asthma Exacerbat & Regulat, Borstel, GermanyRes Ctr Borstel, Div Mucosal Immunol & Diagnost, Borstel, Germany
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Univ Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil
Simoneti, C. S.
Ferraz, E.
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Reg Univ Ctr Espirito Santo do Pinhal, Espirito Santo Do Pinhal, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil
Ferraz, E.
de Menezes, M. B.
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Univ Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil
de Menezes, M. B.
Bagatin, E.
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Univ Estadual Campinas, Dept Prevent & Social Med, Fac Med Sci, Campinas, SP, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil
Bagatin, E.
Arruda, L. K.
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Univ Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil
Arruda, L. K.
Vianna, E. O.
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Univ Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, BrazilUniv Sao Paulo, Med Sch Ribeirao Preto, Dept Med, Ribeirao Preto, Brazil