Bioaerosols - more than just allergens: complex situations at workplaces Our breathing air does not only contain gases but also plenty of airborne particles of organic origin. These particles could affect the upper or lower respiratory tract in exposed persons and may cause irritative, toxic and/or allergic complaints. Up to now no quantification methods are available to assess the effects of bioaerosols on humans. In susceptible subjects the inhalation of allergens can be characterized by the induction of an IgE-mediated Type I sensitization. For non-allergenic components of organic dust no test systems exist that allows to assess the effect on exposed subjects. Besides indoor air exposure, especially the often quantitatively higher bioaerosol exposure at several workplaces plays an important role. For example, in agriculture, textile industry or at waste disposal workplaces complex bioaerosol exposure with variable composition occurs. Particularly with regard to the inflammatory and pyrogenic effects induced by bioaerosol inhalation only little information is available. This article summarizes options and their limits to characterize components of organic dust beyond their allergenic properties.
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China Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, North Nanjing St 155, Shenyang 110001, Liaoning, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, North Nanjing St 155, Shenyang 110001, Liaoning, Peoples R China
Li, Xu
Ma, Xiaochun
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China Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, North Nanjing St 155, Shenyang 110001, Liaoning, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Intens Care Unit, North Nanjing St 155, Shenyang 110001, Liaoning, Peoples R China
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Harvard Med Sch, Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Ctr Immunol & Inflammatory Dis, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Ctr Immunol & Inflammatory Dis, Boston, MA 02115 USA
Chen, Song
Luster, Andrew D.
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Harvard Med Sch, Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Ctr Immunol & Inflammatory Dis, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Ctr Immunol & Inflammatory Dis, Boston, MA 02115 USA
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Sheba Med Ctr, Diagnost Imaging, Tel Hashomer, Israel
Tel Aviv Sourasky Med Ctr, Tel Aviv, IsraelCharite Univ Med Berlin, Campus Charite Mitte, Dept Radiol, Berlin, Germany
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Univ Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, France
CHU Dupuytren, Serv Med Interne A, Limoges, FranceUniv Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, France
Ly, Kim-Heang
Regent, Alexis
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Univ Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, France
Univ Paris 05, Fac Med, Ctr Reference Vascularites Necrosantes & Sclerode, Hop Cochin,Assistance Publ Hop Paris, F-75014 Paris, FranceUniv Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, France
Regent, Alexis
Tamby, Mathieu C.
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Univ Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, FranceUniv Paris 05, INSERM, U1016, Inst Cochin, F-75014 Paris, France