Total synthesis of (3R, 4S)-4-hydroxylasiodiplodin

被引：4

作者：

Nagendra Reddy, G. ^{[1
]}

Gudisela, Mura Reddy ^{[2
]}

Prasad, K. R. S. ^{[1
]}

机构：

[1] Koneru Lakshmaiah Educ Fdn, Dept Chem, Guntur, Andhra Pradesh, India

[2] PS3 Labs LLP, Hyderabad, Telangana, India

来源：

SYNTHETIC COMMUNICATIONS | 2020年 / 50卷 / 15期

关键词：

(3R; 4S)-4-hydroxylasiodiplodin; Lasiodiplodins; Wittig reaction; Yamaguchi esterification and ring-closing metathesis (RCM); RING-CLOSING METATHESIS; BIOLOGICAL EVALUATION; CHEMICAL-SYNTHESIS; LASIODIPLODIN; LACTONES;

D O I：

10.1080/00397911.2020.1774902

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An alternative and concise total synthesis of (3 R, 4S)-4-Hydroxylasiodiplodin has been reported from inexpensive and commercially available 6-heptenal and Orsellinic acid starting materials. The key steps involved in the synthesis are Wittig reaction, Sharpless epoxidation, Yamaguchi esterification and ring-closing metathesis (RCM).

引用

页码：2331 / 2337

页数：7

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