Pathway Commons at Virtual Cell: use of pathway data for mathematical modeling

被引：11

作者：

Blinov, Michael L. ^{[1
]}

Schaff, James C. ^{[1
]}

Ruebenacker, Oliver ^{[1
]}

Wei, Xintao ^{[1
]}

Vasilescu, Dan ^{[1
]}

Gao, Fei ^{[1
]}

Morgan, Frank ^{[1
]}

Ye, Li ^{[1
]}

Lakshminarayana, Anuradha ^{[1
]}

Moraru, Ion I. ^{[1
]}

Loew, Leslie M. ^{[1
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Ctr Cell Anal & Modeling, Farmington, CT 06030 USA

来源：

BIOINFORMATICS | 2014年 / 30卷 / 02期

基金：

美国国家卫生研究院;

关键词：

SYSTEMS; SBML;

D O I：

10.1093/bioinformatics/btt660

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Pathway Commons is a resource permitting simultaneous queries of multiple pathway databases. However, there is no standard mechanism for using these data (stored in BioPAX format) to annotate and build quantitative mathematical models. Therefore, we developed a new module within the virtual cell modeling and simulation software. It provides pathway data retrieval and visualization and enables automatic creation of executable network models directly from qualitative connections between pathway nodes.

引用

页码：292 / 294

页数：3

共 9 条

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