Application of Hydrolase Catalytic Promiscuity in Organic Synthesis

被引：4
作者：
Ge, Xin [1 ]
Lai, Yifeng [1 ,2 ]
Chen, Xinzhi [1 ]
机构：
[1] Zhejiang Univ, Ministiy Educ, Key Lab Biomass Chem Engn, Hangzhou 310027, Zhejiang, Peoples R China
[2] Zhejiang Univ Sci & Technol, Sch Biol & Chem Engn, Hangzhou 310012, Zhejiang, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 33卷 / 08期
关键词：
hydrolase; promiscuity; Michael addition; aldol reaction; three-component reaction; CARBON BOND FORMATION; ONE-POT SYNTHESIS; MICHAEL ADDITION; BIOCATALYTIC PROMISCUITY; ALKALINE PROTEASE; ENZYME PROMISCUITY; SECONDARY-AMINES; LIPASE; DERIVATIVES; CONDENSATION;
D O I：
10.6023/cjoc201212048
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This review introduces the mechanism of hydrolase promiscuity. Several applications of hydrolase catalytic promiscuity in unit reaction, two-step reaction and three-component reaction are summarized, especially for addition, aldol reaction, and Knoevenagel reaction.
引用
收藏
页码：1686 / 1696
页数：11
相关论文
共 51 条
[21]   SYNTHESIS OF OPTICALLY-ACTIVE TRIFLUORINATED COMPOUNDS - ASYMMETRIC MICHAEL ADDITION WITH HYDROLYTIC ENZYMES [J].
KITAZUME, T ;
IKEYA, T ;
MURATA, K .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (17) :1331-1333
[22]   Lipase-catalysed tandem Knoevenagel condensation and esterification with alcohol cosolvents [J].
Lai, Yi-Feng ;
Zheng, Hui ;
Chai, She-Jie ;
Zhang, Peng-Fei ;
Chen, Xin-Zhi .
GREEN CHEMISTRY, 2010, 12 (11) :1917-1918
[23]   Biocatalytic promiscuity: the first lipase-catalysed asymmetric aldol reaction [J].
Li, Chao ;
Feng, Xing-Wen ;
Wang, Na ;
Zhou, Yu-Jie ;
Yu, Xiao-Qi .
GREEN CHEMISTRY, 2008, 10 (06) :616-618
[24]   Promiscuous protease-catalyzed aldol reactions: A facile biocatalytic protocol for carbon-carbon bond formation in aqueous media [J].
Li, Chao ;
Zhou, Yu-Jie ;
Wang, Na ;
Feng, Xing-Wen ;
Li, Kun ;
Yu, Xiao-Qi .
JOURNAL OF BIOTECHNOLOGY, 2010, 150 (04) :539-545
[25]   Protease-catalyzed direct aldol reaction [J].
Li, Hai-Hong ;
He, Yan-Hong ;
Guan, Zhi .
CATALYSIS COMMUNICATIONS, 2011, 12 (07) :580-582
[26]   Lipase-catalysed direct Mannich reaction in water: utilization of biocatalytic promiscuity for C-C bond formation in a "one-pot" synthesis [J].
Li, Kun ;
He, Ting ;
Li, Chao ;
Feng, Xing-Wen ;
Wang, Na ;
Yu, Xiao-Qi .
GREEN CHEMISTRY, 2009, 11 (06) :777-779
[27]   Investigations on enzyme catalytic promiscuity: The first attempts at a hydrolytic enzyme-promoted conjugate addition of nucleophiles to α,β-unsaturated sulfinyl acceptors [J].
Madalinska, Lidia ;
Kwiatkowska, Malgorzata ;
Cierpial, Tomasz ;
Kielbasinski, Piotr .
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2012, 81 :25-30
[28]   A lipase catalyzed condensation reaction with a tricyclic diketone: yet another example of biocatalytic promiscuity [J].
Majumder, Abir B. ;
Ramesh, Namakkal G. ;
Gupta, Munishwar N. .
TETRAHEDRON LETTERS, 2009, 50 (37) :5190-5193
[29]   Network Context and Selection in the Evolution to Enzyme Specificity [J].
Nam, Hojung ;
Lewis, Nathan E. ;
Lerman, Joshua A. ;
Lee, Dae-Hee ;
Chang, Roger L. ;
Kim, Donghyuk ;
Palsson, Bernhard O. .
SCIENCE, 2012, 337 (6098) :1101-1104
[30]   Investigation of lipase-catalyzed Michael-type carbon-carbon bond formations [J].
Strohmeier, Gernot A. ;
Sovic, Tanja ;
Steinkellner, Georg ;
Hartner, Franz S. ;
Andryushkova, Aleksandra ;
Purkarthofer, Thomas ;
Glieder, Anton ;
Gruber, Karl ;
Griengl, Herfried .
TETRAHEDRON, 2009, 65 (29-30) :5663-5668
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