Involvement of annexin V in the entry of influenza viruses and role of phospholipids in infection

被引：38

作者：

Huang, RTC

Lichtenberg, B

Rick, O

机构：

[1] Inst. F. Molekularbiologie und B., Freie Universität, 14195 Berlin

来源：

FEBS LETTERS | 1996年 / 392卷 / 01期

关键词：

influenza virus; binding protein; receptor; annexin; phospholipid;

D O I：

10.1016/0014-5793(96)00783-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Influenza viruses bind to annexin V, a widely spread non-glycosylated phospholipid-binding protein. Externally added phospholipids as well as antiserum against this protein specifically inhibit infection of these viruses in cell. cultures, We conclude that annexin V plays an important role in the entry of these viruses.

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页码：59 / 62

页数：4

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